A new contraceptive option provides a possible answer to an age-old question in family planning: how to address barriers that make it difficult for women to keep using contraception consistently. Results from a PATH study in Uganda published in the journal Contraception, show that self-injection of subcutaneous DMPA* (DMPA-SC, marketed as Pfizer's Sayana® Press) may help women to continue using injectable contraception longer than women who receive traditional intramuscular injections (DMPA-IM) from providers.
‘Self-injection of contraceptive drug may help women to continue using injectable contraception longer than women who receive traditional intramuscular injections from providers.’Over the course of a 12-month study period, 81% of 561 DMPA-SC self-injection participants continued to use the product. Meanwhile, 65% of the 600 women who received DMPA-IM from a health worker continued using the product.
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"In many countries like Uganda, injectable contraception is widely used, but often requires women to return to clinics every three months for injections. As a result, many of them may stop using the method even if they wish to continue," says Dr. Dinah Nakiganda, Assistant Commissioner of Reproductive Health, Uganda Ministry of Health. "Self-injection of DMPA-SC is emerging as an important option for women."
DMPA-SC is an all-in-one injectable contraceptive that puts control of women's reproductive health in their hands. While DMPA-IM is injected into the muscle by a skilled health worker, DMPA-SC combines the drug and needle in the PATH-developed BD Uniject™ injection system--a small, prefilled, autodisable device that is easy for providers with minimal training and for women themselves to administer via self-injection. The branded product Sayana Press is approved for use in more than 40 countries around the world.
In the study, 1,161 women seeking injectable contraception at health facilities were offered the choice of self-injecting DMPA-SC or receiving an injection of DMPA-IM from a health worker. Those who chose self-injection were trained, then given three units to take home along with an instruction guide and reinjection calendar.
At the end of 12 months, significantly more women who self-injected DMPA-SC continued to use the product compared to those who returned to a facility every three months to receive DMPA-IM from a health worker.
"Women and girls have the ability and the right to manage their own sexual and reproductive health needs, and contraceptive self-injection is one new way to make this possible," says Martha Brady, PATH's Reproductive Health Program Leader. "Supporting them to have greater control and decision-making through evidence-based 'self-care' approaches like this can benefit not only women and girls themselves, but health systems overall."
This research was supported by the Bill & Melinda Gates Foundation and the Children's Investment Fund Foundation.
The Uganda study results align with recent research from FHI 360 in Malawi and Planned Parenthood in the United States, both of which found higher continuation for women who self-injected relative to those who received DMPA injections from a health worker. A similar PATH study in Senegal was just completed and those results will be available later in 2018.