Research led by Marsha Moses, PhD, of the Vascular Biology Program at Children's Hospital Boston, has broken new ground in the study of breast cancer. Their investigations prove that a woman's risk of developing breast cancer can be detected much in advance just by few drops of her urine.
In tests, the urine of women with each of two types of breast cancer had markedly elevated levels of certain biomarkers that indicate increased angiogenesis -- known as MMP-9 and ADAM-12 -- as compared with controls.
The discoveries, licensed to the company Predictive Biosciences, may lead to simple "dipstick" tests for breast cancer, catching the disease at the earliest stages or spotting resurgence before it becomes a threat.
Potentially, women whose urine revealed a risk for breast cancer could get more frequent mammograms and make lifestyle changes to minimize the odds.