About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Make Saliva Glands, Tear Glands Using Stem Cells in Lab

by Thilaka Ravi on October 2, 2013 at 7:55 AM
Font : A-A+

Scientists Make Saliva Glands, Tear Glands Using Stem Cells in Lab

Researchers claimed on Tuesday they have created saliva glands and tear glands using stem cells from mice, marking a further advance in the quest to grow replacement bio-engineered organs.

The work shows potential for treatments for malfunctioning glands that cause "dry eye" or "dry mouth" syndromes, which affect tens of millions of people around the world, they said.

Advertisement

A team led by Takashi Tsuji of the Tokyo University of Science grew the glands in the lab dish from precursor cells, and transplanted the primitive organs into mice.

Both transplanted glands knitted well with the adjacent tissue, connecting up to ducts and nerve fibres, they reported.

The lacrimal glands, or tear glands, produced teardrops and the saliva gland responded normally to stimulus from food and protected the mouse against oral infection.
Advertisement

The glands worked over the long term, which in mice is the 18th-month mark, the researchers add.

Failure to lubricate the eyelid, a condition called corneal xerosis, can be dangerous for vision.

Millions of people have xerostomia, where lack of saliva leads to problems in swallowing or mouth infections, the study said.

"Several problems must be solved before the use of bio-engineered secretory glands becomes feasible," Tsuji's team cautioned, pointing to the need to build up a bank of suitable stem cells.

The paper is published in the science journal Nature Communications.

Previous work by the same team has involved "ectodermal" organ regeneration, involving tissue to replenish hair and teeth.

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Stem Cells - Cord Blood Stem Cells - Fundamentals Parkinsons Disease Surgical Treatment Genetics and Stem Cells Bone Marrow Transplantation Watery Eyes Tissue Engineering and Regenerative Medicine Stem Cells Swollen Glands Stem Cell Therapy 

Recommended Reading
Stem Cells - Fundamentals
Encyclopedia section of medindia gives general info about Stem Cells...
Stem Cells - Cord Blood
Encyclopedia section of medindia gives general info about Cord Blood...
Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia (CLL) is one of the most common types of adult leukemia and is ......
Salivary Gland Cancer
Most salivary gland tumors are benign and occur in parotid gland. The most common sign of a ......
Bone Marrow Transplantation
Preferred Term is Hematopoietic stem cell transplantation. In this stem cell from bone marrow are in...
Stem Cell Therapy
Stem cell therapy or regenerative medicine uses undifferentiated cells for the treatment of conditio...
Swollen Glands
Swollen lymph nodes/ Lymphadenopathy is a condition where lymph nodes that are present throughout th...
Tissue Engineering and Regenerative Medicine
This new field is an amalgamation of biology, medicine and engineering, and is believed to have mind...
Watery Eyes
Excess tearing may cause a sensation of watery eyes or result in tears falling down the cheek. Obstr...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use