Medindia LOGIN REGISTER
Medindia
Advertisement

Scientists Identify Hormonal Biomarkers That may Help Predict Menopause Transition

by Rajashri on October 29, 2008 at 3:51 PM
 Scientists Identify Hormonal Biomarkers That may Help Predict Menopause Transition

Certain hormonal biomarkers that may help predict menopause transition in women have been identified by researchers from University of Michigan.

"The information provides a roadmap as to how fast women are progressing through the different elements of their reproductive life," said MaryFran Sowers, professor in the U-M School of Public Health Department of Epidemiology.

Advertisement

The researchers examined the naturally occurring changes in three different biomarkers over the reproductive life of more than 600 women: follicle-stimulating hormone (FSH), anti-Mullerian hormone (AMH) and inhibin B.

They found that the biomarker AMH declined to a very low or non-measurable level five years prior to the final menstrual period.

This decline pinpoints a critical juncture in which a woman probably has so few follicles (eggs) that her fertility becomes increasingly questionable, Sowers said.
Advertisement

They found that the changes in AMH and inhibin B concentrations were predictive of the time to menopause.

The research team also saw changes in FSH, and used the information to identify different reproductive stages

Based on a woman's age and the level of FSH in the blood, researchers were able to describe four different stages that occur for women from their late reproductive period to the time of their final menstrual period.

"People really want information about how long do I have and when will I have my final menstrual period," Sowers said.

"Now we are beginning to say, 'If you have a specific FSH level combined with your age, this is the likelihood that you are in this reproductive stage.'

"We finally have numbers from enough women evaluated over a long time period to describe the reproductive aging process. It begins to give women and clinicians an expanded way to look at menses and endocrine events in terms of reproductive progression," she added.

Source: ANI
RAS/SK
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Women Health News

AI Tool Precisely Detects Postpartum Hemorrhage
An AI tool called Flan-T5 identified postpartum hemorrhage with 95% precision and detected 47% patients with the condition.
Active Scrutiny of Cervical Lesions Fuels Long-Term Cervical Cancer Risk
Active surveillance of cervical lesions was associated with higher cervical cancer risk in the long term compared to its removal.
Contraceptive Pills To Go Over-the-Counter Sale in Japan
Japan initiated the trial of selling morning-after contraceptive tablets over-the-counter in an effort to lower abortion rates and solace for rape victims.
Urinary Tract Infections Surge in Indian Women Due to Ignorance
The rising number of urinary tract infections (UTIs) among Indian women can be attributed primarily to social stigma and a lack of awareness.
Auto-Immune Disease of Pregnancy Linked to Fetal Heart Disorders
Pregnant women with Sjogren's or lupus syndrome have elevated anti-Ro/SSA antibodies which are linked to fetal atrioventricular block in the heart.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Scientists Identify Hormonal Biomarkers That may Help Predict Menopause Transition Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests