A new radioactive bacteria is being developed by scientists that could help treat patients who are suffering from pancreatic cancer.
In lab tests, the modified microbes virtually halted the spreading of pancreatic cancer in mice without harming healthy tissue, the Daily Express reported.
Study Finds Bacteria Shows Promise Against Pancreatic Cancer
Researchers have said that an experimental therapy that uses Listeria bacteria to infect pancreatic cancer cells and deliver tumor-killing drugs has shown promise in lab animal research.
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The bacteria, a weakened form of the Listeria bug, which causes food poisoning, and act like missiles tipped with atomic warheads.
When the bacteria infect cancer cells, they destroy them with blasts of radiation but the emissions are short-lived, so damage is largely confined to the target area.
![Potential Loophole in Pancreatic Cancer Defenses Identified]( "Potential Loophole in Pancreatic Cancer Defenses Identified")
Scientists have identified that pancreatic cancer cells growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control the deadly cancer.
Scientists studied the treatment using mice with a highly aggressive form of pancreatic cancer. They found the bacteria dramatically reduced the cancer's spread, or metastasis.
"We're encouraged that we've been able to achieve a 90 percent reduction in metastases in our first round of experiments," study co-author Dr Claudia Gravekamp, from the Albert Einstein College of Medicine in New York City, said.
The new research builds on previous work that suggested that Listeria may have cancer-fighting potential.
Several years ago scientists found that a weakened form of Listeria monocytogenes bacteria can infect cancer cells while leaving normal cells unharmed. Later they showed that it could be harnessed to carry an anti-cancer drug into tumour cells in laboratory cultures, but the approach was never tested in animals.
The research has been published in the journal Proceedings of the National Academy of Sciences.
Source: ANI
Potential Loophole in Pancreatic Cancer Defenses Identified
Scientists have identified that pancreatic cancer cells growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control the deadly cancer.
Advertisement
Scientists studied the treatment using mice with a highly aggressive form of pancreatic cancer. They found the bacteria dramatically reduced the cancer's spread, or metastasis.
"We're encouraged that we've been able to achieve a 90 percent reduction in metastases in our first round of experiments," study co-author Dr Claudia Gravekamp, from the Albert Einstein College of Medicine in New York City, said.
The new research builds on previous work that suggested that Listeria may have cancer-fighting potential.
Several years ago scientists found that a weakened form of Listeria monocytogenes bacteria can infect cancer cells while leaving normal cells unharmed. Later they showed that it could be harnessed to carry an anti-cancer drug into tumour cells in laboratory cultures, but the approach was never tested in animals.
The research has been published in the journal Proceedings of the National Academy of Sciences.
Source: ANI
New Test Helps in Early Detection of Pancreatic Cancer
Metabolomic analysis - a new diagnostic test could be a safe and easy screening method to detect pancreatic cancer, say researchers.
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Research Probes How Pancreatic Cancers MetastasizeResearchers have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the body. | Advertisement
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Scientists aim to pinpoint particular functional pathways affected by these bacteria that may have an impact on skeletal health.
