About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Decode Molecular Messages That Tell Prostate and Breast Cancers to Spread

by Kathy Jones on May 5, 2013 at 7:16 PM
Font : A-A+

 Scientists Decode Molecular Messages That Tell Prostate and Breast Cancers to Spread

The molecular chatter that ramps certain cancer cells into overdrive and can cause tumors to spread throughout the body has been decoded by scientists at the University of Michigan.

Researchers have long known that tumors recruit healing cells, which is a major reason why cancer is so difficult to thwart. This is the first known study to explain the molecular behavior behind the series of changes that happen in the healing cells that result in metastasis.

Advertisement

Russell Taichman, a professor at the U-M School of Dentistry and research associate Younghun Jung looked at prostate and breast tumors.

Consider that a tumor is a wound that won't heal. To that end, both cancerous and benign tumors emit distress signals and messages to recruit healing-type cells, called mesenchymal stem cells, or MSCs, Taichman said.
Advertisement

"Now we know what messages (tumors) send to recruit and alter those healing cells, and we can take steps to block those messages," said Taichman, the study's principal investigator.

With this information, researchers can now try to develop drugs to pharmaceutically derail tumor formation earlier. This is especially important because this particular molecular signaling involves reactions among proteins that actually make cancer cells more migratory, more aggressive and more likely to spread.

To that end, Taichman said he was surprised at the large role played by the protein CXCL16 in altering the healing type cells in such a way that they revved the cancer cells into overdrive.

"Think of giving a bunch of kids sugar, and they all go nuts," he said.

Their study appeared in the online journal Nature Communications.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Menstrual Disorders
Coffee May Help You Fight Endometrial Cancer
Fermented Skin Care
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Mastitis Prostate Cancer Trans-Urethral Resection of the Prostate Cancer Breasts - Structures and Types Breast Lumps Breast Lumps-Screening Breast Cancer Prostate Cancer: Treatment Options Prostate Specific Antigen [PSA] 

Recommended Reading
Prostate Specific Antigen [PSA]
PSA blood test is specific to prostate gland but not necessarily a cancer specific test but is ......
Prostate Biopsy
Encyclopedia section of medindia gives general information about prostate gland...
Prostate Cancer Screening
PSA (Prostate Specific Antigen) test and Digital Rectal Examination are two tests that allow ......
Breast Cancer
Breast cancer is a cancer that affects the breasts or mammary glands. Early detection and lifestyle ...
Breast Lumps
Most breast lumps are caused by hormonal changes in a woman and may not be cancerous. Common causes ...
Breast Lumps-Screening
Breast lumps must never be neglected but instead be subjected to medical examination to rule out ......
Breasts - Structures and Types
Different stages of breast development in women and an in-depth look at the breast/bust and its ......
Mastitis
Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the ...
Prostate Cancer
This cancer affects men over the age of 50 years and screening with rectal examination and PSA can h...
Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemothe...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)