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Sanitary Lapses at Pharmacy Behind Deadly Meningitis Outbreak in US

by Thilaka Ravi on October 25, 2012 at 12:28 PM
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Sanitary Lapses at Pharmacy Behind Deadly Meningitis Outbreak in US

Significant in-house hygiene issues were reported by US health officials Wednesday while inspecting the Massachusetts compounding pharmacy that sold a steroid preparation linked to a deadly meningitis outbreak.

Investigators found that processes for sterilizing medication at the New England Compounding Center were "not done in conformance with accepted standards," said Madeleine Biondolillo, who leads the northeastern US state's public health department.

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She said that records showed that NECC did not sterilize products for the minimum time required to ensure sterilization, and failed to properly maintain sterilization equipment.

Worse, her office found that on 13 occasions, NECC staff shipped orders from the suspect medication lots before receiving test results confirming that the lots were sterile.
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"Medication was shipped as long as 11 days before the results were received," Biondolillo said.

The unprecedented outbreak of fungal meningitis linked to the contaminated drug has killed 23 people.

The number of infections tied to the tainted steroid rose to 308 in 17 states, the Centers for Disease Control and Prevention reported on its website Tuesday.

Officials have said at least 14,000 people in 23 states could be at risk and that it could be weeks or even months before authorities have a final tally of the infections, due to the disease's long incubation period.

The southern state of Tennessee remains the hardest hit with 70 cases and nine deaths, followed by Michigan with 68 cases and five fatalities.

Other badly hit states include Florida, Indiana, Maryland, New Jersey and Virginia.

The tainted steroid -- typically injected into the spine to treat back pain -- was produced by NECC -- which has since shut down its operations and recalled all of its product.

Source: AFP
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