Saliva Gland Biopsy May Help Diagnose Parkinson's Disease

by VR Sreeraman on January 11, 2013 at 12:58 PM

 Saliva Gland Biopsy May Help Diagnose Parkinson's Disease
A new research has suggested salivary gland biopsy as a diagnostic test for Parkinson's disease.

Parkinson's affects mainly people over 50 years who suffer symptoms such as slowness, which may impede efforts to walk or to stand up, stiffness of muscles (rigidity) and tremors.

"There is currently no diagnostic test for Parkinson's disease," says study author Charles Adler, neurologist with Mayo Clinic in Arizona, US.

"We have previously shown in autopsies of Parkinson's patients that the abnormal proteins associated with Parkinson's are consistently found in the submandibular saliva glands, found under the lower jaw," adds Adler.

"Making a diagnosis in living patients is a big step forward in our effort to understand and better treat patients," says Adler, according to a Mayo Clinic statement.

The study involved a group of people averaging 68 years who had Parkinson's for an average of 12 years. They had responded to Parkinson's medication and would not have known saliva gland disorders.

Biopsies were taken of two different saliva glands: the submandibular gland and the minor saliva glands in the lower lip.

The surgical team was led by Michael Hinni and David Lott, at the Mayo Clinic and the biopsied tissues were tested for evidence of the abnormal Parkinson's protein by study co-author Thomas Beach, with Banner Sun Health Research Institute.

"This procedure will provide a much more accurate diagnosis of Parkinson's disease than what is now available," Beach says.

"One of the greatest potential impacts of this finding is on clinical trials, as at the present time some patients entered into Parkinson's clinical trials do not necessarily have Parkinson's disease and this is a big impediment to testing new therapies," Beach says.

The abnormal Parkinson's protein was detected in nine of the 11 patients who had enough tissue to study. Although Parkinson's disease can't be cured, medications may markedly improve symptoms.

These findings will be presented at the American Academy of Neurology's annual meeting in San Diego in March.

Source: IANS

News A-Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Breast Biopsy Endometrial Biopsy Biopsy-Introduction Prostate Biopsy Biopsy-Specimen Processing Skin Biopsy Nutritional Management of Parkinsons disease 

Recommended Reading
Parkinsons Disease
Parkinson's disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Parkinsons Disease - Surgical Procedure
Parkinson's Disease is a chronic, progressive, brain disorder common among the elderly. It affects ....
Newer Possible Treatment Approaches for Parkinsonís Disease
Researchers at Sweden's Lund University carried out a study on rats to reveal how Parkinson's ......
Sleep Bestows Benefits on Parkinsonís Patients - Study
A new study shows that sleep bestows benefit and improves the motor functioning of people with ......
Encyclopedia section of medindia explains in brief Introduction To Biopsy...
Biopsy-Specimen Processing
Biopsy specimen is processed by either histological section or pathologic examination. Biopsy sampl...
Breast Biopsy
Breast biopsy involves removing a sample of breast tissue to determine whether it is cancerous or .....
Endometrial Biopsy
Encyclopedia section of medindia explains in brief about Endometrial Biopsy...
Nutritional Management of Parkinsons disease
Parkinson's disease is a brain disorder which leads to many other related effects. Nutrition plays a...
Prostate Biopsy
Encyclopedia section of medindia gives general information about prostate gland...
Skin Biopsy
Encyclopedia section of medindia gives general information about skin biopsy....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use