About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Risk of Heart Attack Associated With Various Psoriasis Treatments: Study

by Krishna Bora on August 21, 2012 at 10:58 AM
Font : A-A+

Risk of Heart Attack Associated With Various Psoriasis Treatments: Study

Using Tumor Necrosis Factor (TNF) inhibitors for psoriasis shows significant reduction in risks of heart attack (myocardial infarction), says a report published Online First by Archives of Dermatology, a JAMA Network publication.

"The effect of systemic treatment for psoriasis on cardiovascular disease has been largely unexplored," the authors write as background information in the study. "The primary objective of this study was to assess whether patients with psoriasis treated with TNF inhibitors have a decreased risk of MI [myocardial infarction] compared with those not treated with TNF inhibitors (i.e., those who received oral agents/phototherapy or topical agents)."

Advertisement

Jashin J. Wu, M.D., of the Kaiser Permanente Los Angeles Medical Center, and colleagues, conducted a retrospective study that included patients with at least three ICD-9-CM codes for psoriasis or psoriatic arthritis, without antecedent MI, between January 2004 and November 2010.

Of the 8,845 patients included in the study, 5,075 (57.4 percent) were not treated with any systemic therapy or phototherapy (topical treatment group), 1,673 (18.9 percent) received a TNF inhibitor for at least two consecutive months (TNF treatment group) and 2,097 (23.7 percent) were treated with oral systemic agents or phototherapy (oral/phototherapy treatment group).
Advertisement

After adjusting for other MI risk factors, patients in TNF inhibitor treatment group and the oral/phototherapy treatment group had a significantly lower risk of MI (50 percent and 46 percent, respectively) compared with patients in the topical treatment group. Differences in risk between the TNF inhibitor group and oral/phototherapy group did not reach statistical significance.

"Future prospective studies are needed and warranted to determine whether the use of TNF inhibitors may reduce the risk of major adverse cardiovascular events in patients with systemic inflammatory conditions," the authors conclude.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Top 10 Vitamin B12 Foods for Vegetarians - Slideshow
Targeted Screening Program Beneficial for Prostate Cancer Screening
Are Menopause Symptoms Troubling You?: Try these Options
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Chest Pain Cardiac Catheterization Heart Attack Diet Lifestyle and Heart Disease Coronary Artery Bypass Grafting Stress and the Gender Divide Psoriasis Heart Attack Facts Heart Heart Attack- Lifestyle Risks 

Most Popular on Medindia

How to Reduce School Bag Weight - Simple Tips Blood Pressure Calculator Drug Side Effects Calculator Diaphragmatic Hernia Daily Calorie Requirements Accident and Trauma Care Vent Forte (Theophylline) Loram (2 mg) (Lorazepam) Indian Medical Journals The Essence of Yoga

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use