The study involved 203 women with epilepsy who became
pregnant while taking Topamax. Among the 178 live births that occurred, some
three babies born to mothers who took Topamax and 13 babies born to mothers who
took Topamax and other drugs had major birth defects.
"More research needs to be done to confirm these
results, especially since it was a small study," said researcher John
Craig, MRCP, of the Royal Group of Hospitals in Belfast, Northern Ireland.
The study is
published in the latest issue of the journal Neurology.