Scientists from Queen Mary University of London have invented a
revolutionary device that can significantly lower blood pressure among patients
with uncontrolled high blood pressure.
The device was developed by ROX Medical and named the 'Coupler'. The device is basically a paper clip sized implant, which is inserted between the artery and vein in the upper thigh, in a procedure lasting around 40 minutes under local anaesthetic.
Scientists led a randomised, blinded endpoint clinical trial with patients from multiple European Centres of Hypertension Excellence - including the Barts Blood Pressure Clinic at Barts Health NHS Trust in east London - all of whom had resistant high blood pressure and had not responded to at least three types of drug treatment.
The Coupler also worked well among patients who had failed to respond to renal denervation (another new approach to treating high blood pressure), suggesting the Coupler targets different mechanisms of blood pressure control.
However, patients who had not previously been treated with renal denervation experienced the same level or more of blood pressure reduction. In addition, unlike renal denervation, this new device-based treatment is fully reversible, immediate and pain-free.