About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Retinal Signs can Predict Alzheimer’s Disease

by Karishma Abhishek on November 23, 2020 at 10:32 PM
Font : A-A+

Retinal Signs can Predict Alzheimer’s Disease

Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by a decline in memory and cognition due to the formation of beta-amyloid plaques and tau proteins in the brain tissue.

Similar beta-amyloid peptide changes were noted in the retina, decades earlier than the actual appearance of cognitive decline, by Maya Koronyo-Hamaoui, Ph.D., associate professor of Neurosurgery and Biomedical Sciences and co-corresponding author of the study.

Advertisement


The idea was expanded by the research team at Cedars-Sinai Department of Neurosurgery, published in the journal Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. Retina is a thin layer located at the back of the eyes and is responsible for our vision. It is the direct outgrowth of the central nervous system (brain).

Retinal Signs:

The researchers utilized a non-invasive technique sectoral retinal amyloid imaging to record retinal images in participants, older than 40 years of age with cognitive decline. Peripheral regions of the retina correlate better to the brain damages associated with cognition. Hence the analysis of the retinal images was done using a new process detecting these peripheral regions.
Advertisement

Earlier researches done by Koronyo-Hamaoui had highlighted the role of the retina in predicting the hallmarks signs of AD.

"We found that increased levels of retinal amyloid-beta peptides correlated with levels found in brain tissues, even in the latest stages of Alzheimer's disease. We also suggested a particular type of immune-modulation therapy that may combat the disease by reducing toxic proteins and harmful inflammation in the brain and, in return, enhancing a protective type of immune response that preserved the connections between neurons, which are tightly connected to cognition", said Koronyo-Hamaoui.

This study might contribute to a precise and early diagnosis of Alzheimer's disease, that affects nearly 5.5 million people in the U.S., thereby formulating a novel treatment for the patients.



Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Black Pepper as Preventive Measure Against Omicron
FODMAP Diet: A Beginner's Guide
Smallpox
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Retinal Detachment Common Lifestyle Habits that Cause Diseases Dementia 

Recommended Reading
Alzheimer’s Biomarkers Can Accelerate Down Syndrome Treatment
High levels of Alzheimer's disease biomarkers - Tau and amyloid, discovered in the brain tissue of ....
Quiz On Alzheimer’s Disease
Alzheimer's disease (AD) is the most common form of dementia. Participate in this quiz to find out ....
Does Visual Illusion Explain Enigmatic Human Behavior?
Convolutional neural networks (CNN), an analog to the human visual cortex, are found to be deceived ...
Synthetic DNA Probe: Gateway to Reverse Aging
Bio-compatible synthetic probe - SiR-TTet59B can now be utilized to view the dynamics of telomeres ....
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Dementia
Dementia has become a very big concern as we have an aging population across the world. Dementia is ...
Retinal Detachment
Retinal detachment needs to be treated as soon as possible for good visual recovery. Its surgery in...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use