Medindia
Advertisement

Resveratrol Could Minimize Adverse Effects of Methamphetamine

by Sheela Philomena on November 22, 2013 at 1:26 PM
Font : A-A+

 Resveratrol Could Minimize Adverse Effects of Methamphetamine

Resveratrol - a natural compound found in colored vegetables, fruits may block the effects of methamphetamine, say researchers.

Dennis Miller, associate professor in the Department of Psychological Sciences in the College of Arts and Science and an investigator with the Bond Life Sciences Center, and researchers in the Center for Translational Neuroscience at MU, study therapies for drug addiction and neurodegenerative disorders.

Advertisement

Their research targets treatments for methamphetamine abuse and has focused on the role of the neurotransmitter dopamine in drug addiction.

Dopamine levels in the brain surge after methamphetamine use; this increase is associated with the motivation to continue using the drug, despite its adverse consequences.
Advertisement

However, with repeated methamphetamine use, dopamine neurons may degenerate causing neurological and behavioral impairments, similar to those observed in people with Parkinson's disease.

Miller said that dopamine is critical to the development of methamphetamine addiction-the transition from using a drug because one likes or enjoys it to using the drug because one craves or compulsively uses it, asserting that resveratrol has been shown to regulate these dopamine neurons and to be protective in Parkinson's disease, a disorder where dopamine neurons degenerate; therefore, we sought to determine if resveratrol could affect methamphetamine-induced changes in the brain.

Using procedures established by Parkinson's and Alzheimer's disease research, rats received resveratrol once a day for seven days in about the same concentration as a human would receive from a healthy diet. After a week of resveratrol, researchers measured how much dopamine was released by methamphetamine.

Researchers found that resveratrol significantly diminished methamphetamine's ability to increase dopamine levels in the brain.

The study has been published in Neuroscience Letters.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Anti-ageing and Benefits of Red Wine 

Recommended Reading
Anti-Ageing and Benefits of Red Wine
Ageing process has always been an enigma. Recent research indicates that red wine could delay the .....
Methamphetamine may Fight Flu Virus
Methamphetamine could have flu-fighting properties, suggests research....
Risk of Injecting Drugs Increased By Use Of Crystal Methamphetamine by Street Youth
A study published in CMAJ found that the use of crystal methamphetamine by street-involved yo...
Drug Abuse Screening Test
Drug Abuse Screening Test (DAST) is a screening test to find out if you need professional help with ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use