About Careers Internship MedBlog Contact us

Researchers Provide New Information About the 'Kissing Bug's' Evolution

by Dr. Trupti Shirole on November 19, 2015 at 9:20 PM
Font : A-A+

 Researchers Provide New Information About the 'Kissing Bug's' Evolution

Chagas disease affects about 7-10 million people worldwide. The Center for Disease Control (CDC) estimates that 300,000 people are infected with the illness in the United States alone. It is a major cause of mortality in Latin America and the leading cause of cardiac disease in South and Central America. The vector Rhodnius prolixus, also known as the 'kissing bug' is a major contributor to Chagas disease. An international research team, including scientists from Simon Fraser University, hopes that their study of Rhodnius prolixus will further the development of innovative insect control methods to curb its impact on humans.

Their report, published in PNAS, provides new information about the kissing bug's evolution and molecular biology. Researchers describe large and unique expansions of different gene families that are related to chemoreception (how they detect chemicals), feeding and digestion. Each of these expansions may have facilitated the insect's adaptation to a blood-feeding lifestyle.


SFU biology professor Carl Lowenberger, one of the paper's authors, said, "These are nocturnal, blood-sucking insects that feed on animals and people's faces at night, while we're sleeping."

The feces of infected bugs contains the Chagas-causing parasite, Trypanosoma cruzi. Once feces are deposited, the parasites enter the body cavity through the puncture wounds in the skin. Chagas disease can also be transmitted through blood transfusion, ingesting infected insects or crushing them in fruit juice. Ingestion by wild animals is likely a major route by which the hundreds of reservoir species become infected.

Lowenberger said, "The researchers identified unexpected modifications of important immune pathways and an absence of several components of the IMD pathway. It seems that R. prolixus has a significantly modified immune system, that may have evolved to prevent the elimination of obligate microbial symbionts on which the insect depends on for its survival."

The parasite that causes Chagas disease is transmitted through fecal contamination rather than through the more efficient salivary gland transmission that occurs for other diseases, such as malaria and dengue, which are transmitted by mosquitoes.

An understanding of how the immune factors of R. prolixus potentially retain or eliminate parasites in the insect's body cavity may lead to novel approaches to control or eliminate the disease.

Lowenberger adds understanding the genome may allow researchers to identify kissing bug-specific genes or processes that can serve as targets for new transmission reducing drugs or insecticides.

The research was funded by government agencies from each author's country, including the Natural Sciences and Engineering Research Council of Canada (NSERC). The sequencing was funded by the National Institutes of Health, which approved the research proposal.

More than 100 species of kissing bugs can transmit Chagas disease. Rhodnius prolixus was selected for sequencing because it is a major cause of morbidity and mortality in the Western Hemisphere, and has served as an important model for the study of insect physiology.

The consortium of researchers includes scientists from Canada, USA, Mexico, Guatemala, Colombia, Brazil and Argentina. Researchers hope that the data generated could help alleviate the burden of Chagas disease that traditionally affects the most impoverished people of Latin America.

Source: Eurekalert

News A-Z
What's New on Medindia
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
Quiz on Low-Calorie Diet for Diabetes
World Heart Day in 2022- Use Heart for Every Heart
View all
News Archive
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

Most Popular on Medindia

Find a Doctor Turmeric Powder - Health Benefits, Uses & Side Effects Drug Side Effects Calculator A-Z Drug Brands in India Diaphragmatic Hernia Blood - Sugar Chart Sanatogen Sinopril (2mg) (Lacidipine) Nutam (400mg) (Piracetam) Post-Nasal Drip
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use

Researchers Provide New Information About the 'Kissing Bug's' Evolution Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests