About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Researchers Find Hunger's On/off Switch

by VR Sreeraman on November 7, 2007 at 12:00 PM
Font : A-A+

Researchers Find Hunger's On/off Switch

Australian doctors said Tuesday they had found a molecule that suppresses appetite and in experiments with mice were able to turn it off by injecting an antidote.

The breakthrough by the Sydney team could help cancer patients with wasted bodies put on the weight they need to survive chemotherapy and radiotherapy.

Advertisement

Conversely, spurring on the MIC-1 molecule in overweight people would help them rapidly shed weight.

The research team declared that discovering the role of MIC-1 was an enormous breakthrough after more than 15 years of multi-disciplinary effort. They found that the MIC-1 molecule is a protein that targets the receptors in the brain that switch appetite on or off.
Advertisement

"It's very exciting to be able to work on a therapy that could change lives the way this will," lead researcher Herbert Herzog told The Sydney Morning Herald. "We think that a cancer patient will only have to be injected with the (MIC-1) antibody every three weeks and a person can put on a significant amount of weight in that time which would really help them."

Herzog said a large amount of MIC-1 was produced by cancers and that this was a cause of the dramatic weight loss seen in cancer patients.

Sam Breit, a member of the team, said experiments in mice showed the more advanced the cancer, the stronger the don't-eat message conveyed to the brain.

"This is a very exciting discovery because we have effectively found a new appetite pathway we didn't know existed," Breit said. "It's a breakthrough that could directly improve quality of life for many people."

He said the next step was to find a commercial sponsor and run clinical trials with humans using a synthetic MIC-1 protein.

The findings are published in the journal Nature Medicine.

Source: IANS
SRM/M
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Goji Berries May Protect Against Age-Related Vision Loss
Tapping — A Proven Self-Applied Stress Intervention
Black Pepper as Preventive Measure Against Omicron
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Hungry? - But you Just Ate! Why does your Stomach Growl with Hunger Fullness Factor, Satiety Index and Glycemic Index for Weight Watchers 

Recommended Reading
Study Identifies Brain Circuit Associated With Hunger
Researchers at the University of California, Los Angeles, have identified brain circuits involved .....
Chewing Gum may Help Control Your Hunger Pangs
An easy way to control those hunger pangs would be to pop a chewing gum into your mouth before an .....
Fullness Factor, Satiety Index and Glycemic Index for Weight Watchers
Weight loss is a struggle for many individuals. This can be achieved simply by understanding the ful...
Hungry? - But you Just Ate!
Most of us are tempted by good food, mealtime or not. Once in a way is fine but it is dangerous to g...
Why does your Stomach Growl with Hunger
A rumbling, growly stomach, hiccups and continuous sneezing are some of the body’s signals which we ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)