About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Therapeutic Effects of Deep Brain Stimulation Mechanism in Parkinson’s Patients

by Shirley Johanna on April 15, 2015 at 7:20 PM
Font : A-A+

Therapeutic Effects of Deep Brain Stimulation Mechanism in Parkinson’s Patients

Deep brain stimulation (DBS) is a widely used treatment for people living with Parkinson's disease, but the mechanism of action remains a mystery.

DBS is a surgically implanted device to deliver electrical pulses to inner brain structures involved in movement. Parkinson's disease patients who receive treatment, symptoms of movement, tremor and rigidity diminish when the device is activated, and quickly return if the device is turned off.

Advertisement

Despite the great success of DBS, some significant problems remain. A minority of patients never obtains the full benefit their physicians expect, some patients respond differently to DBS than others.

Researchers at University of California, San Francisco have discovered the mechanism for how DBS exerts its therapeutic effects.

Researchers placed electrodes under the skulls of patients implanted with the DBS device. The activity of the motor cortex was recorded focusing on the synchronization of the signals throughout the brain region. The recordings showed excessive synchronization of activity rhythms in Parkinson's patients.

When DBS was placed in the subthalamic nucleus, when the stimulation reached the motor cortex, synchronization rapidly diminished, as though the neurons have decoupled themselves and are acting independently.





Source: Medindia
Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Medical Gadgets

New Dialysis Device Effectively Treats Severe Liver Failure
A new dialysis device developed by researchers to treat individuals with severe liver failure is safe and effective.
Tiny Video Capsule: A New Hope for Endoscopy
The magnetically controlled capsule endoscopy shows promising results in treating issues related to stomach.
Affordable Smartphone Attachment Enables Convenient Blood Pressure Monitoring
Scientists have developed an affordable, user-friendly clip that utilizes a smartphone's camera and flash to measure blood pressure at the user's fingertip.
 Developing Wireless Patch System to Detect Sleep Apnea at Home
Recent progress in the development of wearable devices has presented alternative ways for sleep monitoring at home, which could be useful in sleep apnea detection.
Non-Invasive Brain Imaging: A Tool to Help Paralysis Patients
Researchers develop non-invasive brain imaging techniques to help people with disabilities.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Therapeutic Effects of Deep Brain Stimulation Mechanism in Parkinson’s Patients Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests