About Careers Internship MedBlog Contact us

Researchers at the Threshold of Creating Anti-ageing Injection

by VR Sreeraman on August 19, 2007 at 2:52 PM
Researchers at the Threshold of Creating Anti-ageing Injection

A month after researchers pin pointed two proteins linked to youth, an injection to erase the health problems associated with ageing is near at hand.

The injection manipulates a body's mitochondria, sausage-shaped 'powerhouses' in every cell of the body except red blood cells. They turn the food we eat into energy that can be used by the heart, muscles, brain and other parts of the body. Research has suggested their deterioration is an important cause of ageing, according to a report in New Scientist magazine.


Correcting genetic mutations in mitochondria can also help fight illnesses such as diabetes, Parkinson's, stroke, Alzheimer's, heart disease and cancer. The gradual build-up of the faulty genes over a lifetime is also thought to be an important cause of ageing. But attempts to introduce normal genes into mitochondria to replace defective ones have so far failed.

"It is not a panacea but, if successful, it might potentially correct part of this age-associated damage to mitochondria which might be important in slowing down ageing," Professor Patrick Chinnery, a leading British expert on mitochondrial disorders, was quoted as saying in Daily Mail.

Mitochondria have their own DNA. If this is faulty a mitochondrial disease occurs.

So far, researchers have been unable to transport genes across the mitochondrial membrane into the mitochondria themselves. In their research, Marisol Corral-Debrinski and colleagues at the Pierre and Marie Curie University in Paris selected two mitochondrial gene mutations - one that causes muscle weakness and another that causes blindness. They tagged normal versions of these genes with two separate 'address codes' and inserted them into cells grown in a lab. Both mutations were reversed.

The experiments would now be conducted on rats, and eventually humans may get the 'elixir of life'.

In a recent trial reported in the Lancet, injections of genes into the brain significantly helped relieve the symptoms of Parkinson's disease.

About one in 5,000 children and adults are at risk of developing a mitochondrial disease, which include disorders of the nervous system and blindness.

Source: IANS
Font : A-A+



Recommended Readings

Latest Research News

Brain Circuits That Shape Bedtime Rituals in Mice
New study sheds light on the intrinsic, yet often overlooked, role of sleep preparation as a hardwired survival strategy.
NELL-1 Protein Aids to Reduce Bone Loss in Astronauts
Microgravity-induced bone loss in space, can be reduced by systemic delivery of NELL-1, a protein required for bone growth and its maintenance.
Connecting Genetic Variants to the Alzheimer's Puzzle
Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells.
Gene Therapy Sparks Spinal Cord Regeneration
Team at NeuroRestore introduces a groundbreaking gene therapy that has effectively promoted nerve regrowth and reconnection, post spinal cord injury.
Unlocking the Gut Microbiome's Influence on Bone Density
Scientists aim to pinpoint particular functional pathways affected by these bacteria that may have an impact on skeletal health.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
Greetings! How can I assist you?MediBot

Researchers at the Threshold of Creating Anti-ageing Injection Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests