Medindia LOGIN REGISTER
Medindia
Advertisement

Research Sheds Light on the Brain's Guardian Cells

by Kathy Jones on April 28, 2013 at 4:56 PM
 Research Sheds Light on the Brain's Guardian Cells

New research by Johan Jakobsson and his colleagues published in Nature Communications sheds light on how the brain's guardian cells work.

Researchers know very little about exactly how microglia work. At the same time, there is a lot of curiosity and high hopes among brain researchers that greater understanding of microglia could lead to entirely new drug development strategies for various brain diseases", says Johan Jakobsson, research group leader at the Division of Molecular Neurogenetics at Lund University. What the researchers have now succeeded in identifying is a deviation in the structure of the microglia cells, which makes it possible to visualise them and study their behaviour.

Advertisement

By inserting a luminescent protein controlled by a microscopic molecule, microRNA-9, the researchers can now distinguish the microglia and monitor their function over time in the brains of rats and mice. It has long been known that microglia form the first line of defence of the immune system in diseases of the brain.

They move quickly to the affected area and release an arsenal of molecules that protect the nerve cells and clear away damaged tissue. New research also suggests that microglia not only guard the nerve cells but also play an important role in their basic function. "This represents a real step forward in technological development. Now we can view microglia in a way that has not been possible before. We and our colleagues now hope to be able to use this technique to study the role of the cells in different disease models, for example Parkinson's disease and stroke, in which microglia are believed to play an important role", explains Johan Jakobsson.



Source: Eurekalert
Font : A-A+

Advertisement

Advertisement
Advertisement

Recommended Readings

Latest Research News

Intricate Dance of Flaxseed, Gut Microbiome, and Breast Cancer Genes
Role of flaxseed in the relationship between gut microorganisms and mammary gland microRNAs has been uncovered by a new study.
MRNA Therapy's Promise for Chronic and Acute Liver Disease
New mRNA stem cell therapy, akin to COVID-19 vaccine tech, shows potential against chronic and acute liver diseases.
Could Light Therapy Be a Breakthrough for Alzheimer's?
Light therapy enhances sleep and psycho-behavioral symptoms in Alzheimer's patients with minimal side effects.
Does Twice Daily Stimulation Enhance Alzheimer's Mental Functions?
Electrical stimulation improves Alzheimer's patients' cognitive function and correlates with restored cortical plasticity.
South Korea's 2050 Forecast: Negative Growth Amid Low Fertility
South Korea's total fertility rate, averaging the number of children a woman aged 15-49 has in her lifetime, dropped to 0.81.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Research Sheds Light on the Brain's Guardian Cells Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests