About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Red Meat Allergy from Tick Bites Could be Higher Than Previously Thought

by Adeline Dorcas on February 25, 2019 at 12:29 PM
Font : A-A+

Red Meat Allergy from Tick Bites Could be Higher Than Previously Thought

Tick bites could pose a risk for developing a red meat allergy than initially suspected, reports a new study.

Until now it has been believed that in order for a tick to trigger an allergic immune response to alpha-gal in humans, the tick would need to have recently fed on the alpha-gal-rich blood of a mammal. New research from the UNC School of Medicine presented at the American Academy of Allergy, Asthma and Immunology (AAAAI) annual conference in San Francisco shows that may not be so.

Advertisement


Alpha-gal is a sugar found in most mammal blood, except humans. When humans develop an allergic immune response to it, this response can lead to a red meat allergy called alpha-gal syndrome (AGS).

"Our original hypothesis was that humans developed the allergy after being exposed to alpha-gal through a tick that had fed on a deer, dog or other small mammal that has alpha-gal," said Dr. Scott Commins, associate professor of medicine and pediatrics at UNC School of Medicine. "This new data suggests that ticks can induce this immune response without requiring the mammal blood meal, which likely means the risk of each bite potentially leading to the allergy is higher than we anticipated."
Advertisement

To reach these findings, researchers stripped white blood cells of their Immunoglobulin E (IgE), antibodies produced by the immune system during an allergic reaction. The stripped white blood cells were then primed with plasma from individuals with AGS and without AGS. Then, researchers added to the cells tick salivary gland extract from four species of ticks - Lone Star, Deer, Gulf Coast, and American Dog. Some of the ticks had recently fed on blood containing alpha-gal, and some had not.

As researchers expected, saliva from the Lone Star and Deer ticks that recently fed on blood caused a reaction. However, saliva from those same types of tick that had not recently fed on blood also caused a reaction. Saliva from a Lone Star tick that had not recently fed caused reactivity 40 times higher compared to the control. Neither type of saliva from the Gulf Coast nor the American Dog ticks caused a reaction.

Because samples of both blood-fed and non-blood-fed tick saliva in these experiments exhibited a range of reactivity, Commins says, "These results suggest that more tick bites than we initially suspected could pose a risk for developing red meat allergy."

There is no treatment for AGS, other than avoiding foods and products that cause a reaction. Commins urges everyone to take precautions to prevent tick bites.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Can Adjusting Fatty Acid Intake Improve Mood in Bipolar Disorder Patients?
Insulin Resistance Doubles the Risk of Major Depressive Disorder
Emotional Healing
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Allergy Phimosis Why Do We Eat - Nutrition Facts Diet Lifestyle and Heart Disease Healthy Living Dealing with Pollen Allergy Remedies for Seasonal Allergy Relief Choose The Right Over-the-Counter Drugs for Allergy Congo Fever Gout and Diet 

Recommended Reading
Allergic Reaction Linked to Tick Bites Often Misdiagnosed as Food Allergy
Those who react to the molecule in red meat, the alpha-gal also have a history of tick bites which ....
Tick Bite Could Trigger Severe Allergy To Red Meat
Being bitten by one of the spider-like bugs can trigger a severe allergy to meat, a new study has .....
New Gel To Protect Against Tick Bite
German researchers have developed a gel that can protect us against tick bites that can result in .....
Cases of Anaphylaxis from Tick Bite Meat Allergy on the Rise
Allergy clinic finds large percentage of anaphylaxis cases from tick bite meat allergy, a recent ......
Allergy
An allergy is a hypersensitive disorder of immune system. Substances that often cause allergic react...
Choose The Right Over-the-Counter Drugs for Allergy
Over-the-counter (OTC) drugs can be bought without a prescription. OTC allergy medications are for t...
Congo Fever
Crimean-Congo Hemorrhagic fever (CCHF) is a viral disease that affects people who are bitten by infe...
Dealing with Pollen Allergy
The plants around you that give you sniffles in your nose at specific time of the year are the sourc...
Gout and Diet
In gout excess of uric acid appears in the blood and its particles are deposited in joints as ......
Phimosis
Phimosis or tight foreskin is the inability to fully retract the foreskin over the glans penis due t...
Remedies for Seasonal Allergy Relief
Understanding the cause and mechanism of seasonal allergy can help in choosing the right treatment. ...
Why Do We Eat - Nutrition Facts
The importance of eating food and the physiological, psychological and social functions of food....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use