New processes that lead to the development of a novel cell implicated in allergies has been discovered by Trinity College Dublin and the United Kingdom researchers. The findings have been published in the leading international journal Nature Immunology.
The work was performed by Professor Padraic Fallon, Science Foundation Ireland Stokes Professor of Translational Immunology of TCD's School of Medicine and Dr Andrew McKenzie of the Medical Research Council Laboratory for Molecular Biology in Cambridge.
The number of people with allergic disease, such as asthma and atopic dermatitis, is increasing globally with Irish children having the fourth highest incidence of asthma in the world. A major area of research in developing new strategies to treat allergic diseases is directed towards increasing understanding of the processes and cells involved that cause allergic inflammation.
This new finding identifies targets for allergic diseases that could be developed into new therapeutic strategies. Professor Fallon's research on allergies is supported by Science Foundation Ireland, The Wellcome Trust, Health Research Board and National Children's Research Centre, Ireland.