55-year-old Mumbai doctor who has liver cancer, and a 36-year-old Kolhapur farmer putting up with end-stage liver failure have successful liver transplants through an exchange of their donor's livers at the Sir HN Reliance Foundation Hospital, an official stated. The four surgeries, performed simultaneously by a team of nearly three dozen surgeons toiling for 14 hours in four operation theatres, finally resulted in the 55-year old medico and 36-year old peasant getting new livers - and a new lease of life said the HNRFH CEO Tarang Gianchandani. "Until four months ago, both patients were oblivious of each other's very existence, little realizing that their destinies could be so closely intertwined and they could have successful liver transplants which would connect them forever," said Gianchandani. ‘In a rare liver swap transplant surgery involving four persons, two donors and two recipients, the lives of a Kolhapur farmer and a Mumbai doctor suffering from end-stage liver failures were saved at the Sir HN Reliance Foundation Hospital, an official stated. ’Read More.. The ailing duo had lost all hopes as the only available family donors, their wives, were of different blood groups. "While the blood groups of one patient (Atam) and his wife were B and A, that of the other patient (Vikram) were A and B, respectively, an exchange of livers donated by each their wives enabled us to transplant both patients and save their lives," said Director and Chief Transplant Surgeon (Dr.) A.S. Soin. Soin added that the biggest challenge in such swap transplants was to perform the surgeries simultaneously on both the donors and the recipients since one or the other donor could back out after their relative receives a transplant. Gianchandani said that besides the HNRFH, only a handful of hospitals in India and abroad have the expertise, infrastructure, and coordination to perform such challenging tasks. Though kidney swaps are common, such exchanges are rare in liver transplantation as the operations are far more intricate taking 8-10 hours each, must be performed with zero error, and besides the blood group, even the liver sizes must match for the donor and the patient. Soin said of the around 3,100 liver transplants at the HNRFH, 43 were swaps in 86 patients, the highest such experience in the world. Now, the hospital is developing an Artificial Intelligence-based exchange algorithm that can match patient-donor pairs to maximize the number of transplants, inter-hospital, and inter-city swap, besides debating the possibility of swaps between different organs, like aliver for kidney'. Director of Gastroenterology and Hepatobiliary Science Chetan Bhatt said in the latest case, both patients were very ill and would not have survived beyond a few months. "The successful exchange is an outstanding example of how sharing of human suffering and joy transcended social barriers and united two families. The swap option is a blessing in times of organ donor shortage," Bhatt pointed out. Gianchandani said three weeks after the swap, the two patients and the donors are convalescing well, put on a normal diet and fast returning to their normal lives.Source: IANS << Vasopressin Cuts Blood Transfusions by Half in Trauma Patien... Scientists Analyze People’s Initial Immune Response to Dengu... >> Recommended Reading Common Types of Liver diseases leading to Liver Transplantation Liver disease that ends in liver failure (end stage liver disease), disrupting several important metabolic functions needs liver transplant for patient survival. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Transplantation Organ and tissue transplantation can give a second chance at life to thousands of people. Learn more about this interesting procedure. READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. 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