Older kidney disease patients who have a high risk of dying while on dialysis may benefit from accepting a so-called extended criteria donor (ECD) kidney-which is more likely to fail than a standard criteria donor kidney-rather than remaining on a transplant wait list. But younger patients and those with short wait times are usually better off holding out for a standard criteria donor kidney. Despite this, some young patients still end up receiving ECD kidneys.
Rajesh Mohandas MD, MPH, Mark Segal MD, PhD (University of Florida), and their colleagues looked to see if demographic factors play a role in whether younger patients accept ECD kidneys. They analyzed all first single-kidney transplants documented in the United States from 2000 to 2009 in patients 18 to 40 years of age and waitlisted less than three years.
Among the major findings:
- Of 13,615 ECD transplants, 591 (4.3%) kidneys went to recipients between 18 and 40 years of age who were waitlisted less than three years.
- African Americans were 1.7 times more likely to receive an ECD kidney than Caucasians.
- Individuals with less education were 2.3 times more likely to receive an ECD kidney than those with a college degree; however, African Americans with higher education levels were not more likely to receive such a lower-quality kidney than Caucasians with college degrees.
"To our knowledge, this is the first report showing that there are racial and social disparities in the quality of allocated transplanted organs. Understanding that such disparities exist is the essential first step to addressing inequalities in health care and to attempt to improve patient outcomes," said Dr. Mohandas. He added that it is important to ensure that kidney transplant candidates are not just informed, but also educated about their choices.
Study co-authors include Michael Casey, MD, Robert Cook, MD, MPH, Kenneth Lamb, PhD, and Xuerong Wen, MS.
Disclosures: The authors reported no financial disclosures.
The article, entitled "Racial and Socioeconomic Disparities in the Allocation of Extended Criteria Donor Kidneys," will appear online at http://cjasn.asnjournals.org/ on October 10, 2013, doi: 10.2215/CJN01430213.
The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.Founded in 1966, and with more than 14,000 members, the American Society of Nephrology (ASN) leads the fight against kidney disease by educating health professionals, sharing new knowledge, advancing research, and advocating the highest quality care for patients.