About My Health Careers Internship MedBlogs Contact us

Quit Smoking To Restore Metabolite Levels

by Hannah Joy on September 23, 2017 at 4:27 PM
Font : A-A+

Quit Smoking To Restore Metabolite Levels

Smokers who quit show remarkable ability in repairing their metabolite levels that resemble exactly to those of nonsmokers, reveals a new study.

Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.


Smoking kills more than 7 million people worldwide annually and is one of the most important risk factors for six of world's eight leading causes of premature death, according to the World Health Organization. But, soon after a person quits the body begins to repair some of accumulated damage caused by smoking.

In fact, according to the U.S. Centers for Disease Control and Prevention, within two to three months of quitting, lung function begins to improve and the risk of heart attack begins to diminish.

A previous study published in 2013 suggested that metabolic changes which occur after smoking cessation may kick start these physiological improvements.

Building on this work, Nikola Pluym and colleagues sought to hone in on what alterations smoking causes in the body's metabolic pathways and whether any of these changes are reversible after quitting.

The researchers regularly collected blood, urine and saliva samples from male volunteers who were trying to quit smoking up to three months after smoking cessation.

To minimize nutritional effects on metabolism, the researchers strictly controlled the volunteers' diets during four in-patient stays.

To ensure compliance, they measured levels of carbon monoxide and cotinine, a nicotine metabolite which can be detected in urine and saliva over several days after someone has smoked.

In the study, the researchers analyzed the experimental samples with an untargeted metabolic fingerprinting approach.

Overall, the researchers identified 52 metabolites that were significantly altered after the subjects stopped smoking, including several that showed reversible changes toward that of a nonsmoker's metabolic profile.

The team concluded that these compounds could one day be used as biomarkers for smoking-induced biological changes. Moreover, the researchers state that the published method would be also useful for evaluating the benefits, if any, for smokers when switching to new products like electronic cigarettes.

Source: Eurekalert

News A-Z
News Category
What's New on Medindia
Turmeric: Magic Ingredient to Keep you Healthy in Winter
Top 7 Benefits of Good Oral Hygiene
Healthy and Safer Thanksgiving 2021
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Health Hazards of Smoking Smoking And Cancer Smoking And Tobacco Diet Lifestyle and Heart Disease Bubbles and Brews - Alcohol Facts Smoking Cigarette Smoking - A Silent Killer Chronic Obstructive Pulmonary Disease Leriche Syndrome Antioxidants to Help You When You Quit Smoking 

Recommended Reading
Running can Help People Quit Smoking
People who joined a running group as part of the community-based program were likely to quit ......
Prescription Smoking-Cessation Drug to Quit Smoking may Not Work Wonders
The introduction of a new prescription smoking-cessation drug varenicline in 2006 had no ......
Running May Help You to Quit Smoking: Report
Having difficulty in quitting smoking? Try Running as it can help. Cigarette smoking is responsible ...
More Than 3300 People Quit Smoking in Several Cities of Virginia State, USA
The percentage of people who stopped smoking was higher in Norfolk than in neighboring Suffolk and ....
Antioxidants to Help You When You Quit Smoking
Smoking is injurious to health, but it sure is a tough addiction to stop. Cure yourself with the pow...
Bubbles and Brews - Alcohol Facts
There is more to alcohol than mere intoxication. Infamous because of its social abuse but indispensa...
Chronic Obstructive Pulmonary Disease
COPD includes respiratory tract disorders that cause obstruction to airflow. These are chronic br...
Cigarette Smoking - A Silent Killer
Smoking kills the smoker silently, pushing him towards serious illnesses, which slowly lead to ......
Health Hazards of Smoking
Smoking causes many diseases and affects the overall health of smokers....
Leriche Syndrome
A patient with Leriche syndrome suffers from claudication symptoms, impotence and decreased pulses i...
Smoking And Cancer
Smoking is the most important preventable cause of cancer in the world....
Smoking And Tobacco
Encyclopedia section of medindia briefs you about the History of Tobacco...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use