Among the drugs used for acute ischemic stroke, recombinant tissue plasminogen activator is widely accepted in the world of medicine. In China, urokinase has been widely used for thrombolysis after acute ischemic stroke. Pro-urokinase is the precursor of urokinase. Compared with urokinase, pro-urokinase has greater ability to dissolve thrombus and is safer to use. However, most countries do not recognize urokinase for thrombolytic treatment after acute ischemic stroke, which has not been approved for clinical use.
Stroke
Stroke can cause permanent disability and it is important to recognize its early warning signs to stop its progress. Early warning signs of stroke include sudden weakness of facial muscles.
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Dr. Wenli Hu and team from Beijing Chao-Yang Hospital, Capital Medical University in China compared the thrombolytic effects of pro-urokinase, recombinant tissue plasminogen activator, and urokinase in a dog model of acute cerebral embolism. They found that jematoxylin and eosin staining showed no hematoma in the infarcted area after thrombolysis with any of the three therapies, and neuronal apoptosis after cerebral infarction was also not attenuated. The results of angiography showed that recanalization after thromboembolism was similar after thrombolysis with pro-urokinase and recombinant tissue plasminogen activator, and that both these drugs were more effective than urokinase. The relevant article was published in the Neural Regeneration Research (Vol. 9, No. 5, 2014).
Source: Eurekalert
Stroke Survivors Need Emotional Support
About 152,000 individuals in England are affected by stroke annually. The repercussions of stroke include both physical disability and emotional stress.
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 Stroke - Top Ten FactsStroke is the third most common cause of death and the most prominent cause of physical deformity in the world | Advertisement
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Quiz on Stroke
Stroke is the third leading cause of death world over. Besides, it also disables the affected people, making them completely dependent on caregivers for their daily needs. Lifestyle greatly affects the chances of developing a stroke. Thus, the incidence of stroke can be brought down to a great extent by leading a healthy lifestyle. Here is a quiz that tests if you know enough about this disabling
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