Use of prenatal vitamins by mothers was associated with a reduced risk for autism spectrum disorder recurrence in young siblings, revealed study.
This study examined whether prenatal vitamin use by mothers was associated with autism spectrum disorder (ASD) recurrence in high-risk families.
The study included 241 children who were selected because a sibling was diagnosed with ASD. Mothers reported their use of prenatal vitamins during pregnancy. While most mothers reported taking prenatal vitamins while pregnant, only 87 (36 percent) mothers met the recommendations to take prenatal vitamins in the six months before pregnancy.
One limitation is that this study was observational, which means there may have been differences between the two groups that weren't accounted for during the analysis, even though the investigators accounted for many factors. Another limitation is the study's relatively small sample size. This study is important because there have been conflicting studies about whether maternal prenatal vitamin use is associated with a lower risk of ASD. More research is needed to confirm the associations observed in this study.
Authors: Rebecca J. Schmidt, Ph.D., of the University of California, Davis, and coauthors (doi:10.1001/jamapsychiatry.2018.3901)
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