About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Prenatal Smoking Raises Asthma Risk in Offspring

by VR Sreeraman on August 17, 2012 at 5:33 PM
Font : A-A+

 Prenatal Smoking Raises Asthma Risk in Offspring

Women who smoke during pregnancy raises the risk of wheezing and asthma in preschool children, warns a new study.

"Epidemiological evidence suggests that exposure to maternal smoking during fetal and early life increases the risk of childhood wheezing and asthma, but earlier studies were not able to differentiate the effects of prenatal and postnatal exposure," said lead author Asa Neuman. MD, of the Institute of Environmental Medicine at the Karolinska Institutet in Stockholm, Sweden.

Advertisement

"Our study, a large pooled analysis of eight birth cohorts with data on more than 21,000 children, included 735 children who were exposed to maternal smoking only during pregnancy."

"These children were at increased risk for wheeze and asthma at preschool age. Furthermore, the likelihood of developing wheeze and asthma increased in a significant dose-response pattern in relation to maternal cigarette consumption during the first trimester."
Advertisement

The eight European birth cohorts included in the study included a total of 21,600 children. Exposure information and information on symptoms of wheeze and asthma were derived from parental questionnaires.

In analyses adjusted for sex, parental education, parental asthma, birth weight and siblings, maternal smoking only during pregnancy was associated with increased risks for wheeze (odd ratio 1.39, 95 % CI 1.08-1.77) and asthma (odds ratio 1.65, 1.18-2.31) at age four to six years. Moreover, maternal smoking during the first trimester of pregnancy, but not during the third trimester or the first year following birth, was associated with increased risks for subsequent wheeze and asthma.

"These results indicate that the harmful effects of maternal smoking on the fetal respiratory system begin early in pregnancy, perhaps before the women is even aware that she is pregnant," said Dr. Neuman.

The study has some limitations, including the use of parental questionnaires to obtain exposure and outcome information.

"Our large pooled analysis confirms that maternal smoking during pregnancy, particularly during the first trimester, is associated with a greater risk of offspring developing wheeze and asthma when they reach preschool age," concluded Dr. Neuman.

"Teens and young women should be encouraged to quit smoking before getting pregnant."

The findings were published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Organ Donation Week 2022 - 'Take the Pledge to Save Lives'
Test your Knowledge on Heart Transplantation
Test Your Knowledge on Lung Transplantation
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Childhood Asthma Asthma Health Hazards of Smoking Smoking And Cancer Smoking And Tobacco Diet Lifestyle and Heart Disease Bubbles and Brews - Alcohol Facts Pregnancy and Antenatal Care Smoking Remedies for Seasonal Allergy Relief 

Most Popular on Medindia

Calculate Ideal Weight for Infants Drug Side Effects Calculator Pregnancy Confirmation Calculator Diaphragmatic Hernia Nutam (400mg) (Piracetam) Selfie Addiction Calculator Daily Calorie Requirements A-Z Drug Brands in India Color Blindness Calculator Find a Doctor
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use