Statisticians have devised a statistical model for predicting what other medical problems a patient might encounter after analyzing medical records from thousands of patients. Like how Netflix recommends movies and TV shows or how Amazon.com suggests products to buy, the algorithm makes predictions based on what a patient has already experienced as well as the experiences of other patients showing a similar medical history.
"This provides physicians with insights on what might be coming next for a patient, based on experiences of other patients. It also gives a predication that is interpretable by patients," said Tyler McCormick, an assistant professor of statistics and sociology at the University of Washington.
The algorithm will be published in an upcoming issue of the journal Annals of Applied Statistics. McCormick's co-authors are Cynthia Rudin, Massachusetts Institute of Technology, and David Madigan, Columbia University.
McCormick said that this is one of the first times that this type of predictive algorithm has been used in a medical setting. What differentiates his model from others, he said, is that it shares information across patients who have similar health problems. This allows for better predictions when details of a patient's medical history are sparse.
For example, new patients might lack a lengthy file listing ailments and drug prescriptions compiled from previous doctor visits. The algorithm can compare the patient's current health complaints with other patients who have a more extensive medical record that includes similar symptoms and the timing of when they arise. Then the algorithm can point to what medical conditions might come next for the new patient.
"We're looking at each sequence of symptoms to try to predict the rest of the sequence for a different patient," McCormick said. If a patient has already had dyspepsia and epigastric pain, for instance, heartburn might be next.
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The statisticians used medical records obtained from a multiyear clinical drug trial involving tens of thousands of patients aged 40 and older. The records included other demographic details, such as gender and ethnicity, as well as patients' histories of medical complaints and prescription medications.
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They came up with a statistical modeling technique that is grounded in Bayesian methods, the backbone of many predictive algorithms. McCormick and his co-authors call their approach the Hierarchical Association Rule Model and are working toward making it available to patients and doctors.
"We hope that this model will provide a more patient-centered approach to medical care and to improve patient experiences," McCormick said.
Source-Eurekalert