Pre-eclampsia has a 1.5-fold to 2-fold higher incidence in first pregnancies, a latest study by researchers at the Mailman School of Public Health and Columbia University Medical Center has revealed.
The condition, which causes complications in approximately 3-6% of all pregnancies, is also associated with high risks of preterm delivery, intrauterine growth restriction, placental abruption, and perinatal mortality. Findings are published online in the British Medical Journal.
The study by Drs. Cande Ananth, Katherine Keyes, and Ronald Wapner in the Departments of Epidemiology and Obstetrics and Gynecology, examined data on 120 million births in the United States between 1980 and 2010 from national hospital discharge surveys. This is the largest cohort study to analyze changes in rates of pre-eclampsia in the U.S.
Why the study is newsworthy:
- The researchers analyzed data collected across 30 years to understand the association of maternal age with time of disease occurrence and mother's date of birth on rates of pre-eclampsia.
- Results suggest that reducing obesity rates could also be favorable to a reduction in pre-eclampsia rates.