Positive Findings of Dasotraline in ADHD in Children Aged 6-12

by Ramya Rachamanti on  February 5, 2019 at 2:27 PM Child Health News
RSS Email Print This Page Comment bookmark
Font : A-A+

Dasotraline showed significant improvement in efficacy compared to placebo at week 1 and throughout the study for children aged 6 to 12 years with attention deficit hyperactivity disorder (ADHD) which could be a promising new treatment.
Positive Findings of Dasotraline in ADHD in Children Aged 6-12
Positive Findings of Dasotraline in ADHD in Children Aged 6-12

A detailed description of the trial design and the results is published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Robert Goldman, PhD, Sunovion Pharmaceuticals (Marlborough, MA and Fort Lee, NJ), and colleagues from Kennedy Krieger Institute/Johns Hopkins University (Baltimore, MD), New York University Langone Medical Center (New York, NY), and Massachusetts General Hospital (Boston, MA) coauthored the article entitled "Dasotraline in Children with Attention-Deficit/Hyperactivity Disorder: A Six-Week, Placebo-Controlled, Fixed-Dose Trial."

The researchers conducted a 6-week trial in which children with a diagnosis of ADHD received a once-daily morning dose of dasotraline (2mg or 4mg) or placebo. The primary endpoint to determine efficacy was an ADHD rating scale that determined change from baseline. Treatment with dasotraline 4g/day only was associated with significant improvement in efficacy.

Dasotraline also showed significant improvement for some secondary efficacy endpoints, including measures of hyperactivity and inattentiveness. The study also assessed the safety of dasotraline treatment and performed subgroup analysis to look for differences in safety and efficacy across subgroups such as age, gender, and use of other treatments for ADHD.

"Over four million children suffer from ADHD. The investigation of new, safe treatments with less side effects is needed for this patient group," says Harold S. Koplewicz, MD, Editor-in-Chief of the Journal of Child and Adolescent Psychopharmacology and President of the Child Mind Institute in New York.



Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

More News on:

Dyslexia Attention Deficit Hyperactivity Disorder (ADHD) Height and Weight-Kids Bullying at School - Tips For Schools ADHD Dyscalculia / Learning Disabilities Diet to control Attention Deficit Hyperactivity Disorder Mind-wandering Adult Attention-Deficit Hyperactivity Disorder (ADHD) Temper Tantrum in Children 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Find a Doctor

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive