Medindia
Advertisement

Positive Findings of Dasotraline in ADHD in Children Aged 6-12

by Ramya Rachamanti on February 5, 2019 at 2:27 PM

Positive Findings of Dasotraline in ADHD in Children Aged 6-12

Dasotraline showed significant improvement in efficacy compared to placebo at week 1 and throughout the study for children aged 6 to 12 years with attention deficit hyperactivity disorder (ADHD) which could be a promising new treatment.

A detailed description of the trial design and the results is published in the Journal of Child and Adolescent Psychopharmacology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Advertisement


Robert Goldman, PhD, Sunovion Pharmaceuticals (Marlborough, MA and Fort Lee, NJ), and colleagues from Kennedy Krieger Institute/Johns Hopkins University (Baltimore, MD), New York University Langone Medical Center (New York, NY), and Massachusetts General Hospital (Boston, MA) coauthored the article entitled "Dasotraline in Children with Attention-Deficit/Hyperactivity Disorder: A Six-Week, Placebo-Controlled, Fixed-Dose Trial."

The researchers conducted a 6-week trial in which children with a diagnosis of ADHD received a once-daily morning dose of dasotraline (2mg or 4mg) or placebo. The primary endpoint to determine efficacy was an ADHD rating scale that determined change from baseline. Treatment with dasotraline 4g/day only was associated with significant improvement in efficacy.
Advertisement

Dasotraline also showed significant improvement for some secondary efficacy endpoints, including measures of hyperactivity and inattentiveness. The study also assessed the safety of dasotraline treatment and performed subgroup analysis to look for differences in safety and efficacy across subgroups such as age, gender, and use of other treatments for ADHD.

"Over four million children suffer from ADHD. The investigation of new, safe treatments with less side effects is needed for this patient group," says Harold S. Koplewicz, MD, Editor-in-Chief of the Journal of Child and Adolescent Psychopharmacology and President of the Child Mind Institute in New York.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Dyslexia Attention Deficit Hyperactivity Disorder (ADHD) Height and Weight-Kids Bullying at School - Tips For Schools ADHD Dyscalculia / Learning Disabilities Diet to control Attention Deficit Hyperactivity Disorder Mind-wandering Adult Attention-Deficit Hyperactivity Disorder (ADHD) Temper Tantrum in Children 
Recommended Reading
Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is a neurobiological disorder that affects normal be...
Diet to control Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is a neurological disorder that affects children of ...
Dyscalculia / Learning Disabilities
Dyscalculia is a learning disability involving mathematics. Recognized by The WHO, it affects nearl...
Dyslexia
Dyslexia is a reading disability that occurs when the brain does not properly recognize and process ...
Mind-wandering
Mind wandering is a spontaneous and unintentional shifting of attention of thoughts from a primary t...
Temper Tantrum in Children
Temper tantrum is an attention seeking behavior in young children who cannot control or express thei...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use