Peripheral artery disease(PAD) patients were found to have low Omega-3 index compared to those without this disease, according to new research published in Lipids.
PAD is a disease that affects the blood vessels outside the heart and brain. Evidence from other studies suggests that omega-3s affect many steps of the atherosclerotic process. More specifically, they improve endothelial function; promote vasodilatation through relaxation of smooth muscle cells; exert antioxidant, anti-inflammatory, and antithrombotic actions; delay development of plaques and increase their stability; and decrease wall stiffening.
Peripheral Artery Disease (PAD)
Peripheral arterial disease is a chronic condition marked by deposition of fatty plaque within arteries of the body and reduction in blood supply.
Advertisement
‘Minute reduction in Omega-3 Index found to increase the risk peripheral artery disease. Omega- 3 helps to lower inflammatory burden, warding off the development of PAD.’
Read More..
Tweet it Now
Read More..
Because PAD is essentially atherosclerosis of the leg arteries, researchers in this study believe that patients with PAD may have an omega-3 fatty acid deficiency.
To study the relationship between the Omega-3 Index and PAD, the investigators compared the Omega-3 Index in 145 patients with PAD to 34 controls without PAD.
They found that the Omega-3 Index was significantly lower in the PAD patients than the controls (5% vs 6%). When they controlled for other patient characteristics that might have influenced these findings (like age, smoking, blood pressure, diabetes, drugs, etc.), the Omega-3 Index was still lower in the cases vs. the controls.
In the final analysis, for every 1% unit reduction in the Omega-3 Index, the odds of being a PAD patient increased by 39%, and for every additional pack-year of smoking the odds of being a PAD case increased by 4%.
"It is likely that the lower inflammatory burden associated with a higher Omega-3 Index may be part of the explanation for these results," said Bill Harris, Ph.D., one of the study's authors. "Whether long-term use of omega-3 supplements and/or increased consumption of oily fish could prevent the development of PAD should be examined in future studies."
Source: Eurekalert
Advertisement
They found that the Omega-3 Index was significantly lower in the PAD patients than the controls (5% vs 6%). When they controlled for other patient characteristics that might have influenced these findings (like age, smoking, blood pressure, diabetes, drugs, etc.), the Omega-3 Index was still lower in the cases vs. the controls.
In the final analysis, for every 1% unit reduction in the Omega-3 Index, the odds of being a PAD patient increased by 39%, and for every additional pack-year of smoking the odds of being a PAD case increased by 4%.
"It is likely that the lower inflammatory burden associated with a higher Omega-3 Index may be part of the explanation for these results," said Bill Harris, Ph.D., one of the study's authors. "Whether long-term use of omega-3 supplements and/or increased consumption of oily fish could prevent the development of PAD should be examined in future studies."
Source: Eurekalert
Advertisement
Advertisement
|
Advertisement
Recommended Reading
Latest Research News
Link between chromosome length and biological aging marker discovered. The finding helps explain why people with longer telomeres have a lower dementia risk.
Integrated structural biology helps discover how the cystic fibrosis transmembrane conductance regulator (CFTR) works.
Link between advanced paternal age and higher risks for reproductive and offspring medical problems has been discovered.
Can gene astrology predict disease risk? Yes, your genes can determine your future health and disease risk.
Injury to the white matter explains why football players are at an increased risk for cognitive and behavioral problems later in life.