About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Parkinson's Disease Induce Fatigue Is Linked With Lower Diastolic Blood Pressure

by Jeffil Obadiah on August 23, 2019 at 4:17 PM
Font : A-A+

Parkinson's Disease Induce Fatigue Is Linked With Lower Diastolic Blood Pressure

Fatigue symptoms in Parkinson's disease are related to an insignificant but constant slump in diastolic blood pressure.

Scientists in the Journal of Parkinson's Disease say that PD is a slowly progressive disorder that affects movement, muscle control, and balance. It is the second most common age-related neurodegenerative disorder affecting about 3% of the population by the age of 65 and up to 5% of individuals over 85 years of age. Fatigue is a disabling non-motor symptom that affects about half of all individuals with PD. A 2015 systematic review on this topic confirmed the absence of high-quality evidence supporting any particular PD fatigue treatment.

Advertisement


"The majority of people with PD consider fatigue, defined as diminished energy levels or increased perception of effort that is disproportionate to attempted activities, to be one of their three biggest symptomatic concerns. But despite its high prevalence and disabling nature, we know relatively little about its underlying causes," explained lead investigator Vikas Kotagal, MD, MS, Department of Neurology,

University of Michigan and Veterans Affairs Ann Arbor Health System (VAAAHS) and GRECC, Ann Arbor, MI, USA. "Understanding the biological basis for fatigue in PD is a key step towards designing effective treatments. This is an important goal for the field of PD clinical research."
Advertisement

Investigators conducted a cross-sectional study research assessment of 35 people with PD recruited from the Ann Arbor Veterans Affairs Health System, all of whom wore a 24-hour blood pressure monitor to track their blood pressure hourly while they were at home. Researchers asked participants about the presence of fatigue symptoms and grouped them into two categories: those with fatigue and those without. The data demonstrate study participants with fatigue symptoms had lower mean DBP compared to those without fatigue. The differences were most notable in the morning.

"This is a novel finding that we hope may open the door for new, currently untapped ways to treat fatigue symptoms in PD," commented Dr. Kotagal. "We hope these results will help move us towards better treatments for PD fatigue. If we can design and test treatments that increase DBP without worsening the harmful cardiovascular effects of high systolic blood pressure (SBP), we may be able to improve fatigue symptoms in PD. Our data may also have implications on the off-target side effects of some classes of antihypertensive medications when used by patients with PD and fatigue."

SBP, the top number typically given when blood pressure values are presented, is commonly used to describe people's blood pressure because it is a good marker for atherosclerosis and cardiovascular disease. It often gets more attention than DBP, which is typically presented at the bottom. DBP gets comparatively less attention but may better reflect the type of autonomic dysfunction that is common in PD.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Health Benefits of Giloy
Breast Cancer Awareness Month 2021 - It's time to RISE
First-Ever Successful Pig-To-Human Kidney Transplantation
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Thalassemia Chronic Fatigue Syndrome Top Health Tips to Overcome Tiredness Tired All The Time Chronic Fatigue Symptom Evaluation Blood in Stools - Symptom Evaluation Bombay Blood Group Top Ten Reasons Why You Should Eat Breakfast Asthenia Drug That Can Make You Feel Tired 

Recommended Reading
Nutritional Management of Parkinsons disease
Parkinson's disease is a brain disorder which leads to many other related effects. Nutrition plays ....
Parkinsons Disease
Parkinson's disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...
Wolff-Parkinson-White Syndrome (WPW)
Wolff-Parkinson-White syndrome is caused due to an extra electrical pathway in the heart, which ......
Eye Twitching - Blepharospasm
Uncontrolled muscle twitching occurs in this condition, though benign it may need further ......
Asthenia
Asthenia refers to lack of muscle strength and extreme debility. A healthy lifestyle and early diagn...
Blood in Stools - Symptom Evaluation
Blood in stools results from bleeding that arises from any part of the digestive tract. Causes of bl...
Bombay Blood Group
Bombay blood group is a rare blood type in which the people have an H antigen deficiency. They can r...
Chronic Fatigue Symptom Evaluation
The causes of chronic fatigue are quite diverse, and vary from simple overexertion to heart disease ...
Chronic Fatigue Syndrome
Information about Chronic fatigue syndrome, or yuppie flu, which is a complex disorder, characterize...
Thalassemia
Thalassemia is an inherited blood disorder passed on through parental genes causing the body to prod...
Tired All The Time
Tired All The Time (TATT) syndrome is not only about feeling of tired, however there are a host of o...
Top Health Tips to Overcome Tiredness
If you follow a healthy lifestyle and still feel tired, you should rule out all possible medical cau...
Top Ten Reasons Why You Should Eat Breakfast
Side effects of skipping breakfast are inefficient brain and body functioning. This unhealthy habit ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use