Positive airway pressure (PAP) therapy improves a number of important neurobehavioral outcomes in children with sleep apnea syndrome, shows study.

The findings were published online ahead of print publication in the American Thoracic Society''s American Journal of Respiratory and Critical Care Medicine.
In the prospective study, 52 children (mean age 12 ±4 years) with OSAS, 10 of whom had significant developmental delays, underwent neurobehavioral assessments of sleepiness, behavioral problems, attention and quality of life at baseline and after three months of PAP treatment. Adherence with PAP treatment varied widely, with an average use of 170+145 minutes per night.
PAP treatment was associated with significant improvements in attention deficits, behavior, sleepiness and caregiver- and child-reported quality of life. Improvements in sleepiness scores, but not in other outcomes, were significantly correlated with adherence. Similar improvements in behavioral scores were seen in the subset of children with developmental delays. Among subjects younger than seven (mean age 4.5 ±1.7 years), significant improvements were seen in sleepiness and OSAS-specific quality of life.
"OSAS in children is known to be associated with behavioral disturbances and learning deficits, but the effects of PAP therapy on these deficits have not been studied," said Dr. Marcus. "Our study is the first to demonstrate that PAP therapy results in significant improvements in a range of neurobehavioral domains in these patients, including those with developmental delays."
The study had several limitations, including the lack of a placebo group, the use of reports from subjects and caregivers only, and the lack of blinding.
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Source-Newswise