In the horrifying incident, the 17-year-old Taslim Solangi, who was eight-months pregnant was thrown to dogs by her father-in-law and gave birth to her baby prematurely.
Condemning incident, Senator Semeen Siddiqui demanded an inquiry into the incident.
PML-Q senators staged a token walkout in protest against the incident, while others joined the protest.
Condemning the incident, Leader of the House Raza Rabbani also said that he would take the House into confidence on the incident after getting information from the Sindh chief minister.
The baby born prematurely was thrown into the nearby Ubhal Wah canal by the killer father-in-law.
Meanwhile, reports also suggest hit men had been dispatched to Karachi to kill the absconding mother of Taslim who had fled the village.
In Islamabad, President Asif Ali Zardari reacted sharply to the report of killing of the girl and asked lady MNA Nafeesa Shah to investigate the shocking event and submit him a report.
President's spokesman Farhatullah Babar said that he was greatly disturbed over the incident and had immediately asked Nafeesa Shah to investigate the matter.