About Careers MedBlog Contact us

Pain Processing is Elevated in Patients with Mild to Moderate Alzheimer's Disease

by Dr. Trupti Shirole on June 1, 2015 at 10:39 AM
Font : A-A+

Pain Processing is Elevated in Patients with Mild to Moderate Alzheimer's Disease

It is a common belief that cognitively impaired people have reduced pain sensitivity. However, analysis of previous studies on pain responses in cognitively impaired patients has revealed that the experience of pain is elevated in patients with mild to moderate Alzheimer's disease.

Researcher Ruth Defrin from University of Tel Aviv, Israel, said, "It appears that those with widespread brain atrophy or neural degeneration...all show increased pain responses and/or greater pain sensitivity. However, individuals with cognitive impairment can have difficulty communicating the features of their pain to others, which in turn presents a significant challenge for effective diagnosis and treatment of their pain."


The researchers are unclear on the pain sensitivity in late Alzheimer's disease. They said, "The effects of other types of neurodegenerative impairment on pain processing appear variable. Pain responses seem to be decreased in patients with frontotemporal dementia and Huntington's disease, but increased in those with Parkinson's disease. Effects on pain sensitivity may vary even for diseases affecting similar areas of the brain."

The study also suggested that various developmental disabilities, such as autism, cerebral palsy, and intellectual disability, are also associated with increased pain sensitivity. These findings suggest that pain processing is frequently altered in cognitively impaired individuals, often with increased sensitivity to painful stimuli.

The study was published in PAIN.

Source: Medindia


Recommended Reading

Latest Research News

 Regrowth of Nerve Cells Could Heal Certain Types of Blindness and Paralysis
Researchers found that treatments helping to repair nerve damage in neurons in a near-embryonic state might potentially restore sight and movement.
What Are the Effects of Smoking on Quality of Life?
Tobacco smoke contains toxic chemicals which damage lungs, weaken the immune system and cause tuberculosis.
 Brain Shape Controls Our Thoughts, Feelings, and Behaviour
Identifying an unappreciated relationship between brain shape and activity overturns the century-old paradigm emphasizing the importance of complex brain connectivity.
Eight Threats to Black Adult's Longevity
Decoding the eight factors affecting Black adults' life expectancy.
Beyond the Campus: Contrasting Realities Revealed!
Sobering truth about foot travel in the United States emerges from international statistics, highlighting the prevalence of walking on the Blacksburg campus.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Pain Processing is Elevated in Patients with Mild to Moderate Alzheimer's Disease Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests