About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Osteoporosis Treatment Helped by Protein

by Rathi Manohar on September 28, 2010 at 8:37 PM
Font : A-A+

 Osteoporosis Treatment Helped by Protein

Methods to treat age-related osteoporosis could be developed with the help of a protein discovered by scientists at Tokyo Medical and Dental University, Japan.

Osteoporosis is characterized by reduced bone mass and increased risk of fracture - an imbalance created by decrease in formation of bone forming osteoblast cells from mesenchymal cells upon aging. Instead, these cells form more fat cells.

Advertisement

Hiroshi Takayanagi and colleagues found that the gene regulatory protein Maf promoted mesenchymal cell generation of osteoblasts and suppress their generation of fat cells.

On the other hand, mice lacking Maf showed delayed bone formation. Furthermore, Maf levels were found to decrease in mouse mesenchymal cells upon aging and to be reduced by increased oxidative stress, something that occurs upon aging.

Scientists believe that these data could lead to new approaches to treat age-related osteoporosis.

Source: ANI
Advertisement
Advertisement
Advertisement

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Osteoporosis Treatment Helped by Protein Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests