Researchers have traced the age and origin of the E280A gene mutation responsible for early-onset Alzheimer's in a Colombian family with an unusually high incidence of the disease to a single founder dating from the 16th century. Kenneth S. Kosik, Harriman Professor in Neuroscience at UC Santa Barbara and co-director of the campus's Neuroscience Research Institute (NRI), conducted the study. The findings appear in the journal Alzheimer's & Dementia. "Some mutations just increase your risk, but this mutation is not a risk," Kosik said. "This mutation is highly penetrant, which means that if you carry the mutation, you will get early-onset Alzheimer's disease." Source: Eurekalert << Now, Anti-Microbial Cell Phone Cases may Help Keep Diseases... Crocodiles are Cleverer Than Previously Thought: University... >> Recommended Reading Risk Factors for Alzheimers Disease Cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease. READ MORE Alzheimers Disease Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others. READ MORE Cystic Fibrosis Cystic fibrosis is a genetic disease involving the mucus and sweat glands and the medical world has still to find its cure READ MORE Diet and Alzheimer´s Disease Alzheimer''s begins with forgetfulness, but over time affects speech and coordination along with drastic behavioral changes. The right diet may lower your risk by 40%. So isn''t a diet change worth it? READ MORE DNA Finger Printing DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases. READ MORE Genetics of Alzheimer´s disease There are numerous genes that have been discovered that are associated with Alzheimer’s disease and indicate increased risk, aiding genetic counseling and better care. READ MORE Inherited Breast Cancer Syndromes Inherited breast cancers are caused due to mutations in genes that increase the risk of breast cancer in women. READ MORE McArdle Disease McArdle disease is a genetic disorder in which the body cannot breakdown glycogen in the muscles. It also known as McArdle syndrome or Glycogen storage disease type V (GSD-V). READ MORE Von Hippel-Lindau Disease / Rare Genetic Disorder Von Hippel-Lindau Disease (VHL) or Von Hippel-Lindau Syndrome is a rare genetic disorder caused by a mutation in the VHL gene. It is characterized by the development of benign tumors and cysts in multiple organs. READ MORE Weaver Syndrome Weaver syndrome is a genetic disorder in which children show accelerated bone growth, advanced bone age and a characteristic appearance of the face. READ MORE Most Popular on Medindia The Essence of Yoga Blood - Sugar Chart Selfie Addiction Calculator More News on: Alzheimers DiseaseDNA Finger PrintingCystic FibrosisMcArdle DiseaseWeaver SyndromeDiet and Alzheimer´s DiseaseGenetics of Alzheimer´s diseaseInherited Breast Cancer SyndromesVon Hippel-Lindau Disease / Rare Genetic Disorder
Researchers have traced the age and origin of the E280A gene mutation responsible for early-onset Alzheimer's in a Colombian family with an unusually high incidence of the disease to a single founder dating from the 16th century. Kenneth S. Kosik, Harriman Professor in Neuroscience at UC Santa Barbara and co-director of the campus's Neuroscience Research Institute (NRI), conducted the study. The findings appear in the journal Alzheimer's & Dementia. "Some mutations just increase your risk, but this mutation is not a risk," Kosik said. "This mutation is highly penetrant, which means that if you carry the mutation, you will get early-onset Alzheimer's disease." Source: Eurekalert << Now, Anti-Microbial Cell Phone Cases may Help Keep Diseases... Crocodiles are Cleverer Than Previously Thought: University... >> Recommended Reading Risk Factors for Alzheimers Disease Cognitively normal adults exhibiting atrophy of their temporal lobe or damage to blood vessels in the brain are more likely to develop Alzheimer's disease. READ MORE Alzheimers Disease Alzheimer's disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others. READ MORE Cystic Fibrosis Cystic fibrosis is a genetic disease involving the mucus and sweat glands and the medical world has still to find its cure READ MORE Diet and Alzheimer´s Disease Alzheimer''s begins with forgetfulness, but over time affects speech and coordination along with drastic behavioral changes. The right diet may lower your risk by 40%. So isn''t a diet change worth it? READ MORE DNA Finger Printing DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases. READ MORE Genetics of Alzheimer´s disease There are numerous genes that have been discovered that are associated with Alzheimer’s disease and indicate increased risk, aiding genetic counseling and better care. READ MORE Inherited Breast Cancer Syndromes Inherited breast cancers are caused due to mutations in genes that increase the risk of breast cancer in women. READ MORE McArdle Disease McArdle disease is a genetic disorder in which the body cannot breakdown glycogen in the muscles. It also known as McArdle syndrome or Glycogen storage disease type V (GSD-V). READ MORE Von Hippel-Lindau Disease / Rare Genetic Disorder Von Hippel-Lindau Disease (VHL) or Von Hippel-Lindau Syndrome is a rare genetic disorder caused by a mutation in the VHL gene. It is characterized by the development of benign tumors and cysts in multiple organs. READ MORE Weaver Syndrome Weaver syndrome is a genetic disorder in which children show accelerated bone growth, advanced bone age and a characteristic appearance of the face. READ MORE Most Popular on Medindia The Essence of Yoga Blood - Sugar Chart Selfie Addiction Calculator More News on: Alzheimers DiseaseDNA Finger PrintingCystic FibrosisMcArdle DiseaseWeaver SyndromeDiet and Alzheimer´s DiseaseGenetics of Alzheimer´s diseaseInherited Breast Cancer SyndromesVon Hippel-Lindau Disease / Rare Genetic Disorder
