The study involved women enrolled in a large cohort study that examined factors affecting disease in women. Researchers analyzed the data obtained from 70,928 women who had reported about their health, diet and medical reports every two years from 1992 for an around 11.5 years.
It was seen that nearly 64.8% of them were on HRT at least once. Analysts found about 2819 incident of cholecystectomies and 2608 of those patients were on HRT.
Moreover, those were on oral HRT were at a much higher risk for gallbladder disease and consequent removal of gallbladder than those who took oral HRT.
These findings fall in line with previous studies reporting the increased risk of gallbladder disease with HRT in menopausal women.