The celebrity American talk show host has described her battle with fatigue and weight gain in the October issue of O Magazine.
"First hyperthyroidism, which sped up my metabolism and left me unable to sleep for days. (Most people lose weight. I didn't.) Then hypothyroidism, which slowed down my metabolism and made me want to sleep all the time,' she said.
Experts believe that the talk show host is talking about Hashimoto's disease.
"Although she has not officially revealed her exact diagnosis, it sounds like chronic autoimmune thyroiditis or Hashimoto's disease," explains Samara Ginzburg, M.D., assistant professor of medicine and endocrinology at the Albert Einstein College of Medicine in New York.
"Hashimoto's can start with a hyperthyroid phase, due to release of stored hormone from an inflamed gland, followed by a hypothyroid phase." She said.
"As with other autoimmune diseases (in which the body's immune system mistakenly attacks healthy tissues), it's believed that female hormones play some role in thyroid diseases. Just how big a role is not known. Puberty, pregnancy, and menopause, all seem to affect the onset of thyroid diseases," said Rita Baron Faust, a health educator and author of "The Autoimmune Connection."
Despite the large number of people suffering from thyroid conditions, millions walk around without a proper diagnosis.
"The key is for women to know about these symptoms and to report them fully to their doctors or other health care providers, because when viewed individually doctors often dismiss them as isolated problems or examples of normal aging," said Martha Nolan, vice president of public policy for the Society for Women's Health Research, and a thyroid disease patient, who had the condition for five years before it was properly diagnosed. "Patients need to put the symptoms together, speak up and doctors need to pay attention."
Thyroid disease can be easily diagnosed with a simple blood test and treatment is usually successful. It may require lifelong thyroid hormone replacement therapy or radiation and surgery, depending on the type of condition.
"Hashimoto's disease is diagnosed with blood testing for TSH (thyroid function) and thyroid autoantibodies," explains Dr. Ginzburg. "It is treated with daily thyroid replacement in the form of levothyroxine."
The trick in managing thyroid disease is getting a proper diagnosis.
"Women who are gaining or losing weight without trying, experiencing depression or anxiety without some external trigger, and have symptoms such as palpitations, hair loss or joint pain, should not blame them on pregnancy or menopause," says Baron Faust.
"It's true that mood swings, palpitations, and difficulty concentrating are symptoms of menopause, but they are also red flags for thyroid disease," Faust added.