Chinese researchers at Nantong University say that testing the expression of a protein called TSPAN1 in tissues can prove useful in evaluating the prognosis of colorectal cancer patients.
In a recent study, published in the World Journal of Gastroenterology, the researchers investigated the association between this protein and human colorectal adenocarcinoma.
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Colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer is the third most common cancer in men.
Colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer is the third most common cancer in men.
The researcher further revealed that 88 specimens of human colorectal adenocarcinoma were surgically removed.
TSPAN1 protein levels in cancer tissues were determined by immunohistochemistry using a polyclonal antibody against self-prepared TSPAN1.
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Dr. Zhu and colleagues say that patients with TSPAN1 protein over expression were found to have a significantly shorter survival period than that in patients with TSPAN1 protein negative or weak expression, respectively.
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Based on their observations, the researchers came to the conclusion that testing TSPAN1 expression in tissues would be a useful tool to evaluate the prognosis of patients with colorectal cancer.
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