AIDS Patient Got More Than Thirty SARS-CoV-2 Mutations Within Her Body
Researchers found that SARS-CoV-2 (COVID-19) virus underwent more than thirty mutations in an African AIDS patient.
Researchers found that SARS-CoV-2 (COVID-19) virus underwent more than thirty mutations in an African AIDS patient.
‘The human proteins METTL3, YTHDF1, and YTHDF3 are crucial for the replication of coronavirus inside our body. A synthetic molecular inhibitor of METTL3 called STM2457, at its highest dosage, suppressed the multiplication of SARS-CoV-2 by more than 90%’
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Digging deeper into this helped experts convert the strength of SARS-CoV-2 into its weakness. The team found that two additional proteins, YTHDF1 and YTHDF3 , were also crucial in the viral replication inside our body. They then partnered with the UK-based Storm therapeutics and experimented with finding the best-matching compound that blocks and inactivates METTL3.
On comparing the effect of STM2457, a METTL3 inhibitor with an inactive control compound called STM2120 against the cells infected by HCoV-OC43 (an animal flu virus) and SARS-CoV-2, they found that,
Opaganib Helps Treat Moderate-to-severe COVID-19
Opaganib is a medication with potential anticancer, anti-inflammatory, and antiviral activities. It showed excellent efficacy in reducing the need for supplemental oxygen in COVID-19 patients.
Opaganib is a medication with potential anticancer, anti-inflammatory, and antiviral activities. It showed excellent efficacy in reducing the need for supplemental oxygen in COVID-19 patients.
• STM2457 in the exact dosage suppressed the multiplication of SARS-CoV-2 by more than 90%
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�Happy Hypoxia� may Cause Death in COVID-19
One of a prime and defying reason for COVID mortality is “Happy Hypoxia” that renders no significant respiratory distress even at low oxygen levels until the patient reaches fatality.
One of a prime and defying reason for COVID mortality is “Happy Hypoxia” that renders no significant respiratory distress even at low oxygen levels until the patient reaches fatality.
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Test your Knowledge on Coronavirus (COVID-19)
Coronavirus is a large positive-strand RNA virus that is surrounded by a protein envelope. The virus obtains its name from the S protein spikes on its surface, which resemble a crown. The overall pattern of increasing coronavirus cases is shown to spike up with the “second wave” of COVID-19.
With spiking effects of the second wave of coronavirus, the best way to keep it at bay is to follow COVID-appropriate safety practices like wearing a mask, regularly cleaning your hands, and coughing into a bent elbow or tissue along with physical distancing (6 feet about 2 arm's length), that may help evade the severity of COVID-19 infection.
Coronavirus is a large positive-strand RNA virus that is surrounded by a protein envelope. The virus obtains its name from the S protein spikes on its surface, which resemble a crown. The overall pattern of increasing coronavirus cases is shown to spike up with the “second wave” of COVID-19.
With spiking effects of the second wave of coronavirus, the best way to keep it at bay is to follow COVID-appropriate safety practices like wearing a mask, regularly cleaning your hands, and coughing into a bent elbow or tissue along with physical distancing (6 feet about 2 arm's length), that may help evade the severity of COVID-19 infection.
