
Women who are on corticosteroid drugs for asthma or other
chronic diseases do not have an increased risk of delivering babies with birth
defects like oral clefts. This study has
been conducted by the Statens Serum Institute in Copenhagen. Lead researcher
Dr. Anders Hviid said, "No drug can be proven 100 percent safe. However,
our study supports that moderate to large increases in cleft risk can be
excluded."
Researchers studied more than 800,000 babies born in Denmark. They found
that there was no clear link between mothers who use corticosteroids early in
pregnancy and the risk of oral clefts. Although the findings do not prove there
is no risk. Animal studies have proved that corticosteroid drugs can cause oral
clefts, but whether this holds true for humans is yet to be proved.
These findings will be published in the Canadian Medical Association Journal (CMAJ).
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