Researchers from LeukoDx, a company that develops cell based diagnostic technology, have developed a prototype model of white blood cell counter, which requires minimal quantity of blood.
Currently available WBC counters are huge in size and require large blood samples. As most often, differential counts are done manually it takes longer time to get the results.
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The new model, which is the size of briefcase, requires only 5µL of blood and the results are out in few minutes.
The device consists of 50-micrometer-long transparent channel made out of a silicone material with a cross section of only 32 micrometers by 28 micrometers. The small dimensions make sure that only one white blood cell at a time flows through the detection region.
![Genetics Behind White Blood Cell Counts Identified]( "Genetics Behind White Blood Cell Counts Identified")
Among whites 15 gene variants responsible for the diversity of white blood cell counts have been discovered.
The stained blood sample in the detection region is illuminated with a laser, causing it to fluoresce. The resulting emission is then split by a mirror into two beams, representing the green and red fluorescence. The intensity of the emissions for each detected cell is used to determine the differential white blood cell counts.
The device can accurately determine the counts of four common white blood cells, while the rare basophil granulocytes are detected at high levels.
Source: Medindia
Genetics Behind White Blood Cell Counts Identified
Among whites 15 gene variants responsible for the diversity of white blood cell counts have been discovered.
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The stained blood sample in the detection region is illuminated with a laser, causing it to fluoresce. The resulting emission is then split by a mirror into two beams, representing the green and red fluorescence. The intensity of the emissions for each detected cell is used to determine the differential white blood cell counts.
The device can accurately determine the counts of four common white blood cells, while the rare basophil granulocytes are detected at high levels.
Source: Medindia
Leucopenia / Leukopenia
Leucopenia / Leukopenia is a decrease in the number of total white blood cells found in blood. The normal total white cell count is 5000-10000 per cubic millimeter.
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 White Blood Cells Play Key Role in Controlling Red Blood Cell Levels: ResearchersResearchers have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs). | Advertisement
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