Medindia
Advertisement

New Way to Grow Dental Tissue Identified

by Iswarya on June 28, 2019 at 11:42 AM

New Way to Grow Dental Tissue Identified
New cells discovered are probably responsible for the formation of dental tissue, and can be used to grow it for patients, reveals a new study. The findings of the study are published in the International Journal of Applied and Fundamental Research.

FEFU scientists used human prenatal tissues to study the early stage of development of the embryonic oral cavity during the period when the teeth were set up - from the 5th to the 6th week. They have recognized several types of cells that are involved in the formation of one of the teeth rudiments the enamel (dental) organ. Among them, chromophobe cells with elongated spindle-shaped form have been identified which are also responsible for the development of human teeth in the first weeks of embryo formation.
Advertisement


The data obtained can provide a fundamental basis for the development of bioengineering therapies in dentistry and gastroenterology.

'Numerous attempts to grow teeth from only the stem cells involved in the development of enamel, dentin, and pulp, i.e., ameloblasts and odontoblasts, were not successful: there was no enamel on the samples, teeth were covered only by defective dentin. The absence of an easily accessible source of cells for growing dental tissue seriously restricts the development of a bioengineering approach to dental treatment.
Advertisement

To develop technologies of tissue engineering and regenerative medicine, promising methods of treatment in dentistry the cells identified by us may become the clue to the new level of quality dental treatment. Natural implants that are completely identical to human teeth will no doubt be better than titanium ones, and their lifespan can be longer than that of artificial ones, which are guaranteed for 10-15 years.

Although for a successful experiment, we still have a lack of knowledge about intercellular signaling interactions during the teeth development.' said Ivan Reva, Senior Researcher of the Laboratory for Cell and Molecular Neurobiology, School of Biomedicine, FEFU.

The scientist noted that large chromophobe cells reside not only the place where the teeth of the embryo form, but also exist at the border where the multilayers squamous epithelium of the oral cavity passes into the cylindrical epithelium of the developing digestive tube. This means that the new bio-engineering approach is relevant not only for growing new dental tissue but also for growing organs for subsequent transplantation and likely will be applied in gastroenterology.

The development of new biological approaches for the teeth reconstruction with stem cells is one of the most pressing tasks in dentistry for the upcoming years. There are still a lot of questions challenging the researchers.

For example, scientists have yet to figure out how in the earliest stages of human embryo development, from the seemingly homogeneous, and in fact, multilayered ectoderm, which is located in the forming oral cavity, different types and forms of teeth develop. However, it is already clear that more kinds of cells are engaged in the earliest stages of human teeth formation than it was previously supposed.

Thanks to the research of FEFU scientists in cooperation with their colleagues from Russia and Japan, it also became clear that the crown of the tooth and its root have different mechanisms of formation.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
Plant-Based Diet may Reduce the Risk of COVID-19
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Tooth Decay Tooth Discoloration Teeth Chart Dental Check-Up Root Canal Treatment Toothache Quiz on Dental Care Dental Care during Pregnancy Neck Cracking 

Recommended Reading
Stem Cells Successful In Regrowing Center Of The Tooth
Stem cells have successfully been used in growing the pulp-dentine complex, the structure which ......
Bone Growth from Implanted Tooth and Dental Pulp Stem Cells Proved Through Cell Transplantation
Researchers in Japan have completed a study showing that stem cells derived from deciduous canine .....
Home Remedies to Fix a Broken or Cracked Tooth
Do you have a broken or cracked tooth? Here are a few natural home remedies that can help you fix a ...
Sparkling White Teeth | How to Get White Teeth Naturally?
Did you know that you could flash a wide smile with sparkling white teeth without spending a ......
Dental Care during Pregnancy
Dental care is not only safe but also essential during pregnancy. Hence, it is important for you to ...
Dental Check-Up
It is commonly recommended that you visit the dentist twice a year to clean your teeth and gums and ...
Neck Cracking
Neck cracking or neck popping is caused by quick movements to loosen the ligaments and joints of the...
Root Canal Treatment
Root Canal Treatment or Endodontic therapy is a procedure done to remove the infected pulp and save ...
Tooth Decay
Tooth decay in toddlers, children and adults, also called dental caries, is a bacterial infection ca...
Tooth Discoloration
Tooth discoloration or staining is caused commonly due to smoking, some medicines and poor dental .....
Toothache
Toothache or pain in the tooth is one of the most dreaded and bothersome symptom and those who have ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use