New Therapy Helps Treat Severe Asthmatic Cough

Despite treatment with high-dose inhaled corticosteroids, long-acting β2-agonists, and leukotriene-receptor antagonists, the patient's cough had worsened and was awakening her at night and disturbing her conversations.

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Since all conventional treatments seemed to fail, the researchers used bronchial thermoplasty to treat all visible bronchi.

The patient had three procedures at 3-week intervals.

The cough improved immediately after the first procedure. Three months after the final procedure, the patient had improved in frequency, cough-related quality of life, and asthma control.

The number of capsaicin-induced coughs also decreased, but measures of systemic eosinophilic and airway inflammation and pulmonary function remained unchanged.

The authors conclude that bronchial thermoplasty should be considered in patients with severe asthmatic cough who have not responded to traditional therapeutic approaches.



Source: Eurekalert