Patients with inflammatory bowel disease (IBD) are at greater risk of developing Parkinson disease than those without the disorder, reveals a new study.
Anti-tumor necrosis factor therapy for inflammatory bowel disease was associated with reduced incidence of Parkinson in a new study that analyzed administrative claims data for more than 170 million patients.
Inflammation is a potential biological trigger shared by both inflammatory bowel and Parkinson diseases.
The authors of the study were Inga Peter, Ph.D., of the Ichan School of Medicine at Mount Sinai, New York, and coauthors.
This was an observational study. Researchers were not intervening for purposes of the study and they cannot control natural differences that could explain study findings.
Inflammatory bowel disease (IBD) is defined as a group of autoimmune diseases that are characterized by chronic intestinal inflammation or bowel obstruction resulting from host-microbial interactions or environmental factors.
The two major diseases of this inflammatory condition are ulcerative colitis (UC) and Crohn's disease (CD).