About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

New Therapeutic Target for Type 2 Diabetes Discovered

by Colleen Fleiss on February 9, 2019 at 6:17 PM
Font : A-A+

New Therapeutic Target for Type 2 Diabetes Discovered

Targeted silencing of microRNA-132, which is over expressed in diabetes was found to result in improved insulin secretion and reduced blood glucose in mice and increased insulin secretion in isolated human islet cells, stated researchers.

The new study and promising findings are reported in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers. Click here to read the full-text article free on the Nucleic Acid Therapeutics website through March 7, 2019.

Advertisement


"In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion" is the title of the article coauthored by Roel Bijkerk, Johanne Ellenbroek, Yu Wah Au, Maaike Hanegraaf, Eelco de Koning, and Anton Jan van Zonneveld, Leiden University Medical Center, The Netherlands and Jonathan Esguerra and Lena Eliasson, Lund University and SIS Malmö, Malmö, Sweden.

The researchers treated mice systemically, and mouse and human islets with an agonist designed to block the expression of microRNA-132, called antagomir-132. They reported that blood glucose levels remained low in treated mice for three days following the injection of antogamiR-132. The authors encourage additional studies of this new treatment approach in additional animal models of type 2 diabetes.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
Test  Your Knowledge on Heart
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diabetic Retinopathy Diabetes Diabetic Diet Otitis Media Diabetes - Essentials Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise Stress Relief Through Alternative Medicine Stress and the Gender Divide 

Most Popular on Medindia

Blood Donation - Recipients Blood Pressure Calculator Calculate Ideal Weight for Infants Find a Doctor Hearing Loss Calculator Find a Hospital Selfie Addiction Calculator The Essence of Yoga How to Reduce School Bag Weight - Simple Tips Sinopril (2mg) (Lacidipine)
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

New Therapeutic Target for Type 2 Diabetes Discovered Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests