Pancreatic Proteins — Potential Therapeutic
Generally, one cup of digestive juices (molecules that can break down the food consumed) is produced by the pancreas. In cases where these molecules become activated before they make their way to the gut, they can damage the pancreas itself, thereby digesting the very cells that created them — auto-digestion.
Novel Device Improves Blood Sugar Control Post removal of pancreas
Researchers developed a combination of continuous glucose monitoring, two hormone pumps, and a device known as the bihormonal bionic pancreas (BHBP) to maintain stable glucose levels after removing pancreas.
Researchers developed a combination of continuous glucose monitoring, two hormone pumps, and a device known as the bihormonal bionic pancreas (BHBP) to maintain stable glucose levels after removing pancreas.
‘Lower levels of a protein known as ERRɣ are found to promote auto-digestion of the pancreas (pancreatic enzymes digesting the very pancreatic cells), thereby contributing to pancreatitis (painful inflammation) and pancreatic cancer.
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This may lead to conditions like pancreatitis and pancreatic cancer. Present study finds that pancreatic auto-digestion may be prevented by a protein known as estrogen-related receptor gamma (ERRɣ) in mice. “Our finding provides new insight into both the basic biology of how pancreas cells function, and what might drive pancreatitis and pancreatic cancer,” says Prof. Ronald Evans, director of Salk’s Gene Expression Laboratory, March of Dimes Chair in Molecular and Developmental Biology, and co-senior author of the study.
“The fact that this (ERRɣ) was linked back to patients with chronic pancreatitis suggests that ERR ɣ is clinically relevant and could make a good drug target in the future,” says Evans.
Type 2 Diabetes Remission can Restore Pancreas Size and Shape
Remission of type 2 diabetes has the ability to reverse the shape and size of the pancreas into normal. The insulin production capacity of the pancreas also increases to normal levels.
Remission of type 2 diabetes has the ability to reverse the shape and size of the pancreas into normal. The insulin production capacity of the pancreas also increases to normal levels.
Artificial Pancreas can Prevent Extremely Low Blood Sugar In Diabetic People
New artificial pancreas system can prevent hypoglecemic episodes during and after heavy exercise in people with type 1 diabetes.
New artificial pancreas system can prevent hypoglecemic episodes during and after heavy exercise in people with type 1 diabetes.
New Drug Candidate Improved Insulin Secretion in Diabetics
Increased levels of a microRNA have been identified in type 2 diabetes, which has a negative effect on insulin secretion.
Increased levels of a microRNA have been identified in type 2 diabetes, which has a negative effect on insulin secretion.
