Pancreatic cancer collective comments on new and promising pancreatic cancer treatment.
Lustgarten Foundation and Stand Up To Cancer, strategic partners in the Pancreatic Cancer Collective, offer comments on research published today in the journal Nature Medicine which describes a new therapeutic approach with promise for patients with pancreatic cancer. Based on this research, Martin McMahon, PhD, a cancer researcher at Huntsman Cancer Institute and professor of Dermatology at the University of Utah has received a Pancreatic Cancer Collective New Therapies Challenge Grant.
Pancreatic Cancer
Pancreatic cancer often involves its exocrine part. It grows aggressively, and often detected late. Treatment options include surgery, radiation and chemotherapy.
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‘Scientists have discovered a combination drug therapy that may effectively combat pancreatic cancer. ’
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"In publishing how this new approach of mixing two medicines typically associated with malaria and melanoma can treat pancreatic tumors with KRAS mutations, we are hoping the clinical trial supported by the Pancreatic Cancer Collective's New Therapies Challenge Grant will help us learn how to best administer these medicines, so that we can maximize the benefit for as many patients as possible," said Dr. Tuveson.
"Dr. McMahon's research shows promise as an important advance and was selected in the Pancreatic Cancer Collective as part of the "New Therapies Challenge" for support for further validation as therapy. In this Challenge program, a second round of funding, up to $4 million, is possible to support additional clinical studies to bring new treatments to patients faster," added Phillip A. Sharp, PhD, the Nobel laureate who is chair of SU2C Scientific Advisory Committee (SAC) and scientific co-leader of the Collective.
![Quiz on Pancreatic Cancer]( "Quiz on Pancreatic Cancer")
Pancreatic cancer is often diagnosed at a late stage and can be fatal. Test your knowledge on pancreatic cancer by taking this quiz.
Dr. McMahon's project, "Pancreatic Cancer Collective Research Team: Combined Targeting of MEK1/MEK2 and Autophagy for Pancreatic Cancer" will work toward two goals: 1) elucidating the mechanism(s) by which autophagy is regulated by the RAS pathway, in order to identify predictive biomarkers and new autophagy inhibitors that might be tested in clinical trials; and 2) performing a clinical trial of the T/HCQ combination therapy.
Source: Eurekalert
Quiz on Pancreatic Cancer
Pancreatic cancer is often diagnosed at a late stage and can be fatal. Test your knowledge on pancreatic cancer by taking this quiz.
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Dr. McMahon's project, "Pancreatic Cancer Collective Research Team: Combined Targeting of MEK1/MEK2 and Autophagy for Pancreatic Cancer" will work toward two goals: 1) elucidating the mechanism(s) by which autophagy is regulated by the RAS pathway, in order to identify predictive biomarkers and new autophagy inhibitors that might be tested in clinical trials; and 2) performing a clinical trial of the T/HCQ combination therapy.
Source: Eurekalert
Tongue Microbiome Could Help Early Detection of Pancreatic Cancer
Tongue coat microbiome is altered in pancreatic cancer patients. The change in the degree of colonization of bacteria could help in developing rapid diagnostic methods for early detection of pancreatic cancer.
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 New Combination Blood Test Helps Early Detection of Pancreatic CancerA simple blood test in combination with an existing test help identify pancreatic cancer well before the advanced and difficult-to-treat stages. | Advertisement
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