A study has suggested that a technique that removes additional toxins during dialysis decreases kidney failure patients' risk of dying early. It also reduces patients' risk of dying from heart-related causes or infections.
In light of these results, the technique may become standard for dialysis patients.
Dialysis
Dialysis is an artificial process for removing excess water and waste from the blood. Hemodialysis and peritoneal dialysis are the types of dialysis.
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Retrospective studies suggest that on-line hemodiafiltration (OL-HDF)-which is different from standard dialysis in that it uses so-called high convective transport to remove additional substances over a wide range of sizes-may reduce kidney failure patients' risk of dying prematurely compared with standard hemodialysis. However, results from prospective studies have contradicted this finding.
To investigate the issue further, Francisco Maduell, MD, PhD (Hospital Clinic, in Barcelona, Spain) and his colleagues conducted a multicenter, open-label, randomized controlled trial in which they assigned 906 dialysis patients either to continue hemodialysis or to switch to OL-HDF, with higher convective volume than in previous prospective trials. Patients were followed for three years.
![Haemodialysis and Peritoneal Dialysis Offer Similar Outcomes in Kidney Failure Patients]( "Haemodialysis and Peritoneal Dialysis Offer Similar Outcomes in Kidney Failure Patients")
The results of a recent study suggest that Haemodialysis (HD) and peritoneal dialysis (PD) may offer similar outcomes to patients with end-stage renal disease (ESRD).
Among the major findings over the course of the three-year study:
- Compared with patients who continued on hemodialysis, those assigned to OL-HDF had a 30% lower risk of dying from any cause, a 33% lower risk of dying from cardiovascular-related causes, and a 55% lower risk of dying from an infection.
- The study's findings suggest that switching eight patients from hemodialysis to OL-HDF may prevent one annual death.
- Hospitalizations and dialysis sessions complicated by low blood pressure were lower in patients assigned to OL-HDF.
The findings indicate that OL-HDF may indeed prolong kidney failure patients' lives compared with conventional hemodialysis. "Mortality remains very high in dialysis patients, ranging from 15% to 25% annually. Any reduction of this mortality would be an important achievement," said Dr. Maduell. "In view of this study's results, OL-HDF may become the first-line option in hemodialysis patients," he added.
Source: Newswise
Haemodialysis and Peritoneal Dialysis Offer Similar Outcomes in Kidney Failure Patients
The results of a recent study suggest that Haemodialysis (HD) and peritoneal dialysis (PD) may offer similar outcomes to patients with end-stage renal disease (ESRD).
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Among the major findings over the course of the three-year study:
- Compared with patients who continued on hemodialysis, those assigned to OL-HDF had a 30% lower risk of dying from any cause, a 33% lower risk of dying from cardiovascular-related causes, and a 55% lower risk of dying from an infection.
- The study's findings suggest that switching eight patients from hemodialysis to OL-HDF may prevent one annual death.
- Hospitalizations and dialysis sessions complicated by low blood pressure were lower in patients assigned to OL-HDF.
The findings indicate that OL-HDF may indeed prolong kidney failure patients' lives compared with conventional hemodialysis. "Mortality remains very high in dialysis patients, ranging from 15% to 25% annually. Any reduction of this mortality would be an important achievement," said Dr. Maduell. "In view of this study's results, OL-HDF may become the first-line option in hemodialysis patients," he added.
Source: Newswise
Quiz on Kidney
The kidneys are two bean-shaped organs, each about the size of a fist, and are located just below the rib cage, one on each side of your spine. Healthy kidneys filter about half a cup of blood every minute, removing wastes and extra water to make urine. The urine flows from the kidneys to the bladder through two thin tubes of muscle called ureters, one on each side of your bladder. The
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 Foods to Avoid in Kidney FailureCut back on salt, restrict your fluid intake and limit consumption of proteins if you suffer from kidney failure. | Advertisement
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