Statins, the anti-cholesterol drugs, may help prevent the brain damage that leads to Alzheimer's disease, a new US study has found. Previous research had proposed that people who received statins might be less likely to develop Alzheimer's disease. However, the new study, by researchers at the University of Washington School of Medicine, Seattle, suggests that statins protect the brain against changes that signal the progression of Alzheimer's disease. "Our study is the first to compare the brains of people who had received statins with those who had not," said Gail Li, MD, PhD and the paper's lead author. For the study, the researchers examined the brains of 110 deceased Group Health Cooperative members, aged 65 to 79, who had participated in Adult Changes in Thought (ACT) and who donated their brains for research. The two changes in the brain that are considered the best hallmarks of Alzheimer's are brain "plaques" and "tangles." After controlling for variables including age at death, gender, and strokes in the brain, the researchers found considerably fewer tangles in the brains of people who had taken statins than in those who had not. "These results are exciting, novel, and have important implications for prevention strategies. But they need to be confirmed, because ACT is not a randomized controlled trial," said senior co-author Eric Larson, MD, MPH, the leader of the ACT study and executive director of Group Health Center for Health Studies. A randomized controlled trial of statin treatment and brain autopsy findings would be problematic for ethical and practical reasons, said Dr. Larson. "People with Alzheimer's are diverse. Statins are probably more likely to help prevent the disease in certain kinds of people than others," said Dr Li. "Someday we may be able to know more precisely which individuals will benefit from which types of statins for preventing the changes of Alzheimer's disease," Larson concluded. The findings of the study have been published in the Aug. 28 edition of the journal Neurology. Source: ANISRM/J << High Stress Levels Leads To Memory Decline in People at Risk... Britney Charged for Child Abuse >> Recommended Reading New Study Finds That Statins may Not Protect Against Cancer A new community-based study has challenged an earlier research that claimed statins, a top-selling drug class, worldwide might cut one's risk of developing prostate cancer by reducing READ MORE Male And Over Fifty? - Pop A Statin One of UK's most respected expert in heart diseases , is backing statins all the way. READ MORE Cholesterol Cholesterol is produced by the body (liver) and is essential for normal body functioning. READ MORE Cholesterol - The Enigma Chemical The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is important for the normal metabolism of the body and is dangerous only if present in excess. READ MORE Natural Remedies for Cholesterol – How Effective Are They? Certain natural remedies are effective in controlling high cholesterol, when aided by lifestyle changes. READ MORE Statins Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms but also offering several health benefits. READ MORE Most Popular on Medindia Turmeric Powder - Health Benefits, Uses & Side Effects Drug Interaction Checker Find a Hospital More News on: CholesterolCholesterol - The Enigma ChemicalStatinsNatural Remedies for Cholesterol – How Effective Are They?